KEGG   Delphinapterus leucas (beluga whale): 111185941
Entry
111185941         CDS       T05885                                 
Symbol
PLD2
Name
(RefSeq) phospholipase D2 isoform X1
  KO
K01115  phospholipase D1/2 [EC:3.1.4.4]
Organism
dle  Delphinapterus leucas (beluga whale)
Pathway
dle00564  Glycerophospholipid metabolism
dle00565  Ether lipid metabolism
dle01100  Metabolic pathways
dle04014  Ras signaling pathway
dle04024  cAMP signaling pathway
dle04071  Sphingolipid signaling pathway
dle04072  Phospholipase D signaling pathway
dle04144  Endocytosis
dle04666  Fc gamma R-mediated phagocytosis
dle04724  Glutamatergic synapse
dle04912  GnRH signaling pathway
dle04928  Parathyroid hormone synthesis, secretion and action
dle05200  Pathways in cancer
dle05208  Chemical carcinogenesis - reactive oxygen species
dle05212  Pancreatic cancer
dle05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:dle00001]
 09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    111185941 (PLD2)
   00565 Ether lipid metabolism
    111185941 (PLD2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    111185941 (PLD2)
   04072 Phospholipase D signaling pathway
    111185941 (PLD2)
   04071 Sphingolipid signaling pathway
    111185941 (PLD2)
   04024 cAMP signaling pathway
    111185941 (PLD2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    111185941 (PLD2)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    111185941 (PLD2)
  09152 Endocrine system
   04912 GnRH signaling pathway
    111185941 (PLD2)
   04928 Parathyroid hormone synthesis, secretion and action
    111185941 (PLD2)
  09156 Nervous system
   04724 Glutamatergic synapse
    111185941 (PLD2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    111185941 (PLD2)
   05208 Chemical carcinogenesis - reactive oxygen species
    111185941 (PLD2)
   05231 Choline metabolism in cancer
    111185941 (PLD2)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    111185941 (PLD2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:dle04131]
    111185941 (PLD2)
Enzymes [BR:dle01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.4  phospholipase D
     111185941 (PLD2)
Membrane trafficking [BR:dle04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    111185941 (PLD2)
 Endosome - Golgi transport
  Others
   Others
    111185941 (PLD2)
SSDB
Motif
Pfam: PLDc PLDc_2 PX PH PH_2
Other DBs
NCBI-GeneID: 111185941
NCBI-ProteinID: XP_022451784
UniProt: A0A2Y9PYB2
Position
Unknown
AA seq 933 aa
MAATSESLFPSGGDLDSRQLQMEPDEVDTLKEGEDSADRMHPFLAIYDLQPLKIHPLVFA
PGVPVIAQVVGTERYTSGSKVGTCTLYSVRLTHGDFTWTTKKKFRHFQELHRDLLRHKVL
MSLLPLARFAVAYSPTQEANNRQMPSLPRAGPEGSARHASSKQKYLENYLNRLLTMSFYR
NYHAMTEFLEVSQLSFIPDLGSKGLEGVIRKRSGGHRVPGLTCCGRDQVCYRWSKRWLVV
KDSFLLYMCLETGTITFVQLFDPGFEVQVGKRSTEARYGVRIDTSHRSLILKCSSYRQAR
WWAQEIAELAHGPGRDFVQMHRHESYAPPRPGTLARWFVNGAGYFAAAADAILRAQEEIF
ITDWWLSPEIYLKRPARSDDWRLDIMLKKKAEEGVRVSVLLFKEVELALAINSGYSKKVL
MLLHPNIKVMRHPNQVTLWAHHEKLLVVDQVVAFLGGLDLAYGRWDDLHYRLTDLRDSSE
SASPQPPTSCSDPPATPDLSHNQLFWLGKDYSNLITKDWVQLDRPFEDFIDRETTPRMPW
RDVGVVVHGLPARDLARHFIQRWNFTKTTKAKYKIPRYPYLLPKSTSTANQLPFMLPGVQ
CATVQVLRSVDRWSAGTLENSILNAYLHTIRESQHFLYIENQFFISCSDGRTVLNKVGDE
IVDRILKAHKQGQCFRVYMLLPLLPGFEGDISTGGGNSIQAILHFTYRTLCRGEYSILHR
LKAAMGTAWQDYISICGLRTHGELGRHPVSELIYIHSKMLIADDRTVIIGSANINDRSLL
GKRDSELAVLIEDTEMEASLMNGVEYEAGRFALSLRKHCFSVILGADARPDLDLRDPICD
DFFQSWQDTAESNANIYEQIFRCLPSNAIRSLRALREYVAVEPLATVSPPLARSELTQVQ
GHLVHFPLKFLEDESLLPPLGSKEGVIPLEVWT
NT seq 2802 nt   +upstreamnt  +downstreamnt
atggcggcgacctccgagagcctcttcccctctgggggtgacctggactccagacagtta
cagatggagcccgatgaggtggacactctgaaggagggagaggactcagctgaccggatg
cacccctttctggccatctacgacctccagcctctgaaaattcaccccttggtgtttgcc
cctggggttcccgtcatagcccaggtggtgggcactgaaagatacaccagtggatccaag
gtgggcacctgcactctgtattctgtccgcttgactcacggtgactttacctggacaacc
aagaagaagttccgtcatttccaggaattgcatcgggacctcctgagacacaaagtcttg
atgagtctgctccctctggctcgctttgccgttgcttattctccaacccaagaggcaaac
aacagacagatgccctctctaccccgagcaggtcctgagggctccgccagacatgcatcc
agcaaacagaaatacctggagaattacctcaaccgcctcctgaccatgtctttctaccgc
aactaccatgccatgacagagtttctggaagtcagtcagctgtcctttatcccagacctt
ggatccaaaggactggagggggtgatccggaagcgctcaggtggccaccgtgttcctggc
ctcacctgctgtggccgagaccaagtttgttatcgctggtccaagcggtggctggtggtg
aaggactccttcctgctgtacatgtgcctcgagaccggcaccatcacatttgttcagctc
ttcgaccctggcttcgaggtgcaggtggggaaaaggagcacagaggcacgttacggggtc
cggatcgacacctcccacaggtccttgattctcaagtgcagcagctaccggcaggcacgg
tggtgggcccaggagatcgctgagctggcccatggcccgggcagagactttgtacagatg
caccggcacgaaagctacgctccacctcggcctgggaccctggcccggtggtttgtgaat
ggggcaggttactttgctgctgcagctgatgccatcctgcgagctcaagaggagattttc
atcacagactggtggttgagtcctgagatttacctgaagcgtccggcccgttcggatgac
tggagactggacattatgctcaagaagaaggcggaggagggtgtccgggtgtccgtactg
ctgtttaaggaagtggagttggccttggccatcaacagtggctatagcaagaaggttcta
atgctactgcatcccaacataaaggtgatgcgccacccaaaccaggtgactctgtgggcc
catcatgagaagctcctggtggtggaccaagtagtggccttcttgggggggctggacctc
gcctatggccgctgggatgacctgcactacagactgactgaccttcgggactcctctgag
tcagcttccccccagcctcccacctcatgctcagaccctccagctacaccagacctctct
cacaaccaactcttctggctgggcaaggactacagcaatcttatcactaaggactgggtc
cagctggatcggccttttgaggatttcattgacagggagaccacaccccggatgccatgg
cgggatgtcggggtggtggtccatggcttacccgccagggaccttgcccggcacttcatc
cagcgctggaatttcaccaagaccaccaaggccaagtacaagatacccaggtacccctac
ctgctgcccaagtccaccagcaccgcaaaccagctccctttcatgctcccgggagtgcag
tgcgccaccgtgcaggtcttgcggtcagtggaccgctggtcagcggggaccttggagaac
tccatcctcaatgcctacctgcacaccatcagggagagccagcacttcctctacattgag
aatcaattcttcattagctgctcagatggacggacggtgctgaacaaggtgggcgatgag
attgtggacagaatcctgaaggcccacaaacaggggcagtgcttccgagtctacatgctt
ttgcccctgctccccgggttcgagggcgacatctccacaggtggtggtaactccatccag
gccattctgcacttcacttacaggacgctgtgtcgtggggaatattcaattctacatcgg
ctcaaagcagccatggggacagcgtggcaggactatatttccatctgtgggcttcgcaca
cacggagagctgggtaggcacccggtctcagagctcatctacatccacagtaagatgctc
attgcagatgaccggacagtcatcattggctccgcaaacatcaatgatcggagtttactg
gggaagcgggacagtgagctggccgtgctgatcgaggacacggagatggaggcatccctc
atgaatggtgtggaatatgaggcgggcaggtttgccttgagtttgcggaaacactgcttc
agcgtgattctcggggcagatgcccggccggacctggatctccgagaccctatctgtgat
gacttcttccagtcgtggcaagacacagctgagagcaatgccaatatctatgagcagatc
ttccgctgcctgccgtccaacgccattcgctccctgcgggcactccgggagtatgtggcc
gtggagccgctggccacggtcagccctcccttggcccggtctgaactcacccaggtccag
ggccacctggtccacttccccctcaagttcctggaggatgagtctttgctgccccccctg
gggagcaaggagggcgtgatacccctagaagtgtggacatag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (16)   
   KEGG PATHWAY (16)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (5)   
   UniProt (1)   
   RefSeq(pep) (4)   
DNA sequence (4)   
   RefSeq(nuc) (4)   
Protein domain (5)   
   Pfam (5)   
All databases (49)   

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