KEGG   Drosophila melanogaster (fruit fly): Dmel_CG10079Help
Entry
Dmel_CG10079      CDS       T00030                                 

Gene name
Egfr
Definition
(RefSeq) epidermal growth factor receptor, isoform B
  KO
K04361  epidermal growth factor receptor [EC:2.7.10.1]
Organism
dme  Drosophila melanogaster (fruit fly)
Pathway
dme04013  MAPK signaling pathway - fly
dme04068  FoxO signaling pathway
dme04144  Endocytosis
dme04214  Apoptosis - fly
dme04320  Dorso-ventral axis formation
Brite
KEGG Orthology (KO) [BR:dme00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04013 MAPK signaling pathway - fly
    Dmel_CG10079 (Egfr)
   04068 FoxO signaling pathway
    Dmel_CG10079 (Egfr)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    Dmel_CG10079 (Egfr)
  09143 Cell growth and death
   04214 Apoptosis - fly
    Dmel_CG10079 (Egfr)
 09150 Organismal Systems
  09158 Development and regeneration
   04320 Dorso-ventral axis formation
    Dmel_CG10079 (Egfr)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:dme01001]
    Dmel_CG10079 (Egfr)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:dme04147]
    Dmel_CG10079 (Egfr)
Enzymes [BR:dme01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     Dmel_CG10079 (Egfr)
Protein kinases [BR:dme01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   Dmel_CG10079 (Egfr)
Exosome [BR:dme04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   Dmel_CG10079 (Egfr)
  Exosomal proteins of pancreatic cancer cells
   Dmel_CG10079 (Egfr)
  Exosomal proteins of bladder cancer cells
   Dmel_CG10079 (Egfr)
Cytokine receptors [BR:dme04050]
 Receptor tyrosine kinase
  RTK class I (EGF receptor family)
   Dmel_CG10079 (Egfr)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Pkinase_Tyr Recep_L_domain GF_recep_IV Pkinase Furin-like Kinase-like APH
Motif
Other DBs
NCBI-GeneID: 37455
NCBI-ProteinID: NP_476759
FlyBase: FBgn0003731
UniProt: P04412
Structure
PDB: 

Position
2R
AA seq 1426 aa AA seqDB search
MLLRRRNGPCPFPLLLLLLAHCICIWPASAARDRYARQNNRQRHQDIDRDRDRDRFLYRS
SSAQNRQRGGANFALGLGANGVTIPTSLEDKNKNEFVKGKICIGTKSRLSVPSNKEHHYR
NLRDRYTNCTYVDGNLELTWLPNENLDLSFLDNIREVTGYILISHVDVKKVVFPKLQIIR
GRTLFSLSVEEEKYALFVTYSKMYTLEIPDLRDVLNGQVGFHNNYNLCHMRTIQWSEIVS
NGTDAYYNYDFTAPERECPKCHESCTHGCWGEGPKNCQKFSKLTCSPQCAGGRCYGPKPR
ECCHLFCAGGCTGPTQKDCIACKNFFDEGVCKEECPPMRKYNPTTYVLETNPEGKYAYGA
TCVKECPGHLLRDNGACVRSCPQDKMDKGGECVPCNGPCPKTCPGVTVLHAGNIDSFRNC
TVIDGNIRILDQTFSGFQDVYANYTMGPRYIPLDPERLEVFSTVKEITGYLNIEGTHPQF
RNLSYFRNLETIHGRQLMESMFAALAIVKSSLYSLEMRNLKQISSGSVVIQHNRDLCYVS
NIRWPAIQKEPEQKVWVNENLRADLCEKNGTICSDQCNEDGCWGAGTDQCLTCKNFNFNG
TCIADCGYISNAYKFDNRTCKICHPECRTCNGAGADHCQECVHVRDGQHCVSECPKNKYN
DRGVCRECHATCDGCTGPKDTIGIGACTTCNLAIINNDATVKRCLLKDDKCPDGYFWEYV
HPQEQGSLKPLAGRAVCRKCHPLCELCTNYGYHEQVCSKCTHYKRREQCETECPADHYTD
EEQRECFQCHPECNGCTGPGADDCKSCRNFKLFDANETGPYVNSTMFNCTSKCPLEMRHV
NYQYTAIGPYCAASPPRSSKITANLDVNMIFIITGAVLVPTICILCVVTYICRQKQKAKK
ETVKMTMALSGCEDSEPLRPSNIGANLCKLRIVKDAELRKGGVLGMGAFGRVYKGVWVPE
GENVKIPVAIKELLKSTGAESSEEFLREAYIMASVEHVNLLKLLAVCMSSQMMLITQLMP
LGCLLDYVRNNRDKIGSKALLNWSTQIAKGMSYLEEKRLVHRDLAARNVLVQTPSLVKIT
DFGLAKLLSSDSNEYKAAGGKMPIKWLALECIRNRVFTSKSDVWAFGVTIWELLTFGQRP
HENIPAKDIPDLIEVGLKLEQPEICSLDIYCTLLSCWHLDAAMRPTFKQLTTVFAEFARD
PGRYLAIPGDKFTRLPAYTSQDEKDLIRKLAPTTDGSEAIAEPDDYLQPKAAPGPSHRTD
CTDEIPKLNRYCKDPSNKNSSTGDDETDSSAREVGVGNLRLDLPVDEDDYLMPTCQPGPN
NNNNINNPNQNNMAAVGVAAGYMDLIGVPVSVDNPEYLLNAQTLGVGESPIPTQTIGIPV
MGVPGTMEVKVPMPGSEPTSSDHEYYNDTQRELQPLHRNRNTETRV
NT seq 4281 nt NT seq  +upstreamnt  +downstreamnt
atgctgctgcgacggcgcaacggcccctgccccttccccctgctgctcctgctcctggcc
cactgcatttgcatttggcccgcgtcggcggcccgcgatcgctacgcccgccagaacaat
cgccagcgccatcaggatatagatcgcgatcgggatcgagatcgattcctataccgcagc
agttcggcccaaaatcgacagaggggcggggccaacttcgccctgggactgggagccaac
ggagtcaccattcccaccagtctggaggataagaacaagaacgagttcgtcaaggggaaa
atctgcatcggcactaaatctcggctctccgtgccctccaacaaggaacatcattaccgg
aacctcagagatcggtacacgaactgtacgtatgtggatggcaacctggagctgacctgg
ctgcccaacgagaatttggacctcagcttcctggacaacatacgggaggtcaccggctat
attctgatcagtcatgtggacgttaagaaagtggtatttcccaaactacaaatcattcgc
ggacgcacgctgttcagcttatccgtggaggaggagaagtatgccttgttcgtcacttat
tccaaaatgtacacgctggagattcccgatctacgcgatgtcttaaatggccaagtgggc
ttccacaacaactacaatctctgccacatgcgaacgatccagtggtcggagattgtatcc
aacggcacggatgcatactacaactacgactttactgctccggagcgcgagtgtcccaag
tgccacgagagctgcacgcacggatgttggggcgagggtcccaagaattgccagaagttc
agcaagctcacctgctcgccacagtgtgccggaggtcgttgctatggaccaaagccgcgg
gagtgttgtcacctcttctgcgccggaggatgcactggtcccacgcaaaaggattgcatc
gcctgcaagaacttcttcgacgagggcgtatgcaaggaggaatgcccgcccatgcgcaag
tacaatcccaccacctatgttcttgaaacgaatcctgagggaaagtatgcctatggtgcc
acctgcgtcaaggagtgtcccggtcatctgttgcgtgataatggcgcctgcgtgcgcagc
tgtccccaggacaagatggacaaggggggcgagtgtgtgccctgcaatggaccgtgcccc
aaaacctgcccgggcgttactgtcctgcatgccggcaacattgactcgttccggaattgt
acggtgatcgatggcaacattcgcattttggatcagaccttctcgggcttccaggatgtc
tatgccaactacacgatgggaccacgatacataccgctggatcccgagcgactggaggtg
ttctccacggtgaaggagatcaccgggtatctgaatatcgagggaacccacccgcagttc
cggaatctgtcgtacttccgcaatctggaaacaattcatggccgccagctgatggagagc
atgtttgccgctttggcgatcgttaagtcatccctgtacagcctggagatgcgcaatctg
aagcagattagttccggcagtgtggtcatccagcataatagagacctctgctacgtaagc
aatatccgttggccggccattcagaaggagcccgaacagaaggtgtgggtcaacgagaat
ctcagggcggatctatgcgagaaaaatggaaccatttgctcggatcagtgcaacgaggac
ggctgctggggagctggcacggatcagtgccttacctgcaagaacttcaatttcaatggc
acctgcatcgccgactgtggttatatatccaatgcctacaagtttgacaatagaacgtgc
aagatatgccatccagagtgccggacttgcaatggagctggagcagatcactgccaggag
tgcgtccatgtgagggacggtcagcactgtgtgtccgagtgcccgaagaacaagtacaac
gatcgtggtgtctgccgagagtgccacgccacctgcgatggatgcactgggcccaaggac
accatcggcattggagcgtgtacaacgtgcaatttggccattatcaacaatgacgccaca
gtaaaacgctgcctgctgaaggacgacaagtgccccgatgggtacttctgggagtatgtg
catccacaagagcagggatcgctaaagccattggccggcagagcagtttgccgaaagtgc
catcccctttgcgagctgtgcaccaactacggataccatgaacaggtgtgctccaagtgc
acccactacaagcgacgagagcagtgcgagaccgagtgtccggccgatcactacacggat
gaggagcagcgcgagtgcttccagtgccacccagaatgcaacggttgcactggtccgggt
gccgacgattgcaagtcttgtcgcaacttcaagttgttcgacgcgaatgagacgggtccc
tatgtgaactccacgatgttcaattgcacctcgaagtgtcccttggagatgcgacatgtg
aactatcagtacacggccattggaccctactgtgcagctagtccgccgaggagcagcaag
ataactgccaatctggatgtgaacatgatcttcattatcactggtgctgttctggtgccg
acgatctgcatcctctgcgtggtcacatacatttgtcggcaaaagcaaaaggccaagaaa
gaaacagtgaagatgaccatggctctgtccggctgtgaggattccgagccgctgcgtccc
tcgaacattggagccaatctatgcaagttgcgcattgtcaaggacgccgagttgcgcaag
ggcggagtcctcggaatgggagcctttggacgagtgtacaagggcgtttgggtgccggag
ggtgagaacgtcaagattccagtggccattaaggagctgctcaagtccacaggcgccgag
tcaagcgaagagttcctccgcgaagcctacatcatggcctctgtggagcacgttaatctg
ctgaagctcctggccgtctgcatgtcctcacaaatgatgctaatcacgcaactgatgccg
cttggctgcctgttggactatgtgcgaaataaccgggacaagatcggctctaaggctctg
ctcaactggagcacgcaaatcgccaagggcatgtcgtatctggaggagaagcgactggtc
cacagagacttggctgcccgcaatgtcctggtgcagactccctcgctggtgaagatcacc
gactttgggctggccaagttgctgagcagcgattccaatgagtacaaggctgctggcggc
aagatgcccatcaagtggttggcactggagtgcattcgcaatcgtgtattcaccagcaag
tccgatgtctgggcctttggtgtgacaatttgggaactgctgacctttggccagcgtcca
cacgagaacatccccgctaaggatattcccgatcttattgaagtcggtctgaagctggag
cagccggagatttgttcgctggacatttactgcacacttctctcgtgctggcacttggat
gccgccatgcgtccaaccttcaagcagctgactacggtctttgctgagttcgccagagat
ccgggtcgctatctggccattcccggggataagttcacccggctgccggcctacacgagt
caggatgagaaggatctcatccgaaaattggctcccaccaccgatgggtccgaagccatt
gcggaacccgatgactacctgcaacccaaggcagcacctggtcctagtcacagaaccgac
tgcacggatgagatacccaagctgaaccgctactgcaaggatcctagcaacaagaattcg
agtaccggagacgatgagacggattcgagtgcccgggaagtgggcgtgggtaatctgcgc
ctcgatctaccagtcgatgaggatgattacctgatgcccacatgccaaccggggcccaac
aacaacaacaacataaataatcccaatcaaaacaatatggcagctgtgggcgtggctgcc
ggctacatggatctcatcggagtgcccgttagtgtggacaatccggagtatctgctaaac
gcgcagacactgggtgttggggagtcgccgatacccacccagaccatcgggataccggtg
atgggagtcccgggcaccatggaggtcaaggtgccaatgccaggcagtgagccaacgagc
tccgatcacgagtactacaatgatacccaacgggagttgcagccactgcatcgaaaccgc
aacacggagacgagggtgtag

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (5)   
   KEGG PATHWAY (5)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (83)   
   KEGG ORTHOLOGY (1)   
   RefGene (78)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   FLYBASE (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (7)   
   Pfam (7)   
All databases (108)   

Download RDF
DBGET integrated database retrieval system