KEGG   Drosophila melanogaster (fruit fly): Dmel_CG10523
Entry
Dmel_CG10523      CDS       T00030                                 
Symbol
park
Name
(RefSeq) parkin, isoform B
  KO
K04556  parkin [EC:2.3.2.31]
Organism
dme  Drosophila melanogaster (fruit fly)
Pathway
dme04120  Ubiquitin mediated proteolysis
dme04137  Mitophagy - animal
dme04141  Protein processing in endoplasmic reticulum
Brite
KEGG Orthology (KO) [BR:dme00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    Dmel_CG10523 (park)
   04120 Ubiquitin mediated proteolysis
    Dmel_CG10523 (park)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    Dmel_CG10523 (park)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:dme04131]
    Dmel_CG10523 (park)
   04121 Ubiquitin system [BR:dme04121]
    Dmel_CG10523 (park)
   03029 Mitochondrial biogenesis [BR:dme03029]
    Dmel_CG10523 (park)
Enzymes [BR:dme01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.31  RBR-type E3 ubiquitin transferase
     Dmel_CG10523 (park)
Membrane trafficking [BR:dme04131]
 Autophagy
  Mitophagy
   PINK1-Parkin associated proteins
    Dmel_CG10523 (park)
  Aggrephagy
   Other aggrephagy associated proteins
    Dmel_CG10523 (park)
  Xenophagy
   Other xenophagy associated proteins
    Dmel_CG10523 (park)
Ubiquitin system [BR:dme04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   RBR proteins
    Dmel_CG10523 (park)
Mitochondrial biogenesis [BR:dme03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Parkin-dependent mechanism factors
    Dmel_CG10523 (park)
SSDB
Motif
Pfam: zf-RING_14 IBR_2 zf-RING_12 ubiquitin IBR_1 IBR Rad60-SLD Rcat_RNF216 Dsc3_N Rad60-SLD_2 Ubiquitin_5 Ubiquitin_USP47_N
Other DBs
NCBI-GeneID: 40336
NCBI-ProteinID: NP_730600
FlyBase: FBgn0041100
UniProt: Q7KTX7
Structure
Position
3L:complement(21194754..21196853)
AA seq 482 aa
MSFIFKFIATFVRKMLELLQFGGKTLTHTLSIYVKTNTGKTLTVNLEPQWDIKNVKELVA
PQLGLQPDDLKIIFAGKELSDATTIEQCDLGQQSVLHAIRLRPPVQRQKIQSATLEEEEP
SLSDEASKPLNETLLDLQLESEERLNITDEERVRAKAHFFVHCSQCDKLCNGKLRVRCAL
CKGGAFTVHRDPECWDDVLKSRRIPGHCESLEVACVDNAAGDPPFAEFFFKCAEHVSGGE
KDFAAPLNLIKNNIKNVPCLACTDVSDTVLVFPCASQHVTCIDCFRHYCRSRLGERQFMP
HPDFGYTLPCPAGCEHSFIEEIHHFKLLTREEYDRYQRFATEEYVLQAGGVLCPQPGCGM
GLLVEPDCRKVTCQNGCGYVFCRNCLQGYHIGECLPEGTGASATNSCEYTVDPNRAAEAR
WDEASNVTIKVSTKPCPKCRTPTERDGGCMHMVCTRAGCGFEWCWVCQTEWTRDCMGAHW
FG
NT seq 1449 nt   +upstreamnt  +downstreamnt
atgagttttatttttaaatttattgccacttttgtacgcaaaatgctggagctgttgcaa
tttggagggaaaacccttacgcacacgctgagtatttatgtaaaaacgaacacgggcaaa
acgctgaccgttaatctggagccccagtgggatattaaaaacgtaaaggaactggtggca
ccacaattgggacttcagccggatgatctaaagatcatatttgccggtaaggaactaagc
gatgccacgacaatagagcaatgtgacttgggtcagcaaagcgttttgcatgccattcgt
ttgcgaccgcccgtgcagcgccagaaaatccagtcggccactttggaggaggaggaacct
tcgcttagcgatgaagcctccaagcctctaaatgaaactctgttggacttgcagctggaa
agcgaggagcgtctgaatataaccgatgaagaaagagtccgtgccaaagcgcatttcttt
gtacattgcagccaatgcgataagctgtgtaatggcaaacttcgggtccgctgcgcttta
tgcaagggcggcgcctttactgtccatcgtgatccggagtgttgggatgatgtcttgaag
tcgcgtagaattcccggtcattgtgaaagtctggaggtggcctgcgtggacaacgcggct
ggcgatccgcccttcgctgaattcttcttcaagtgtgctgagcatgtctccggcggggag
aaggattttgcggctccattgaatctaatcaagaataacatcaagaatgttccttgcctg
gcctgcacggatgtgagtgataccgtgttggttttcccctgcgcatcgcagcacgtcacc
tgtatcgactgcttccgccattattgccgttcccgtttgggcgagcgtcagtttatgccg
catccggacttcggctacaccttgccctgtcccgcaggctgcgagcactcgttcatcgag
gagattcatcacttcaagctgttgacacgcgaggagtacgatcggtaccagagattcgcc
accgaggagtatgtcctacaggcaggtggagtactctgcccccagccaggatgcggcatg
ggccttttggtggagcccgattgtcgcaaggtgacatgccagaacggctgtggatacgtg
ttctgccgcaattgtctgcagggctaccatatcggggagtgtctgcccgaggggacgggc
gccagtgccacaaactcctgcgagtacaccgtggacccaaatcgagctgccgaggcgcga
tgggatgaggccagcaatgtcaccatcaaagtcagcacaaagccctgtccaaaatgcaga
acccccacggagcgagatggcggttgcatgcacatggtctgcacacgcgctggctgcgga
ttcgagtggtgctgggtctgccagactgagtggacacgcgactgcatgggagcccactgg
ttcggctaa

  All links  
Gene (201)   
   RefGene (197)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   FLYBASE (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
3D Structure (3)   
   PDB (3)   
Protein domain (12)   
   Pfam (12)   
All databases (222)   

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