KEGG   Drosophila melanogaster (fruit fly): Dmel_CG6489
Entry
Dmel_CG6489       CDS       T00030                                 

Gene name
Hsp70Bc
Definition
(RefSeq) Heat-shock-protein-70Bc
  KO
K03283  heat shock 70kDa protein 1/2/6/8
Organism
dme  Drosophila melanogaster (fruit fly)
Pathway
dme03040  Spliceosome
dme04141  Protein processing in endoplasmic reticulum
dme04144  Endocytosis
dme04213  Longevity regulating pathway - multiple species
Brite
KEGG Orthology (KO) [BR:dme00001]
 09120 Genetic Information Processing
  09121 Transcription
   03040 Spliceosome
    Dmel_CG6489 (Hsp70Bc)
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    Dmel_CG6489 (Hsp70Bc)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    Dmel_CG6489 (Hsp70Bc)
 09150 Organismal Systems
  09149 Aging
   04213 Longevity regulating pathway - multiple species
    Dmel_CG6489 (Hsp70Bc)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:dme01009]
    Dmel_CG6489 (Hsp70Bc)
  09182 Protein families: genetic information processing
   03041 Spliceosome [BR:dme03041]
    Dmel_CG6489 (Hsp70Bc)
   03009 Ribosome biogenesis [BR:dme03009]
    Dmel_CG6489 (Hsp70Bc)
   03110 Chaperones and folding catalysts [BR:dme03110]
    Dmel_CG6489 (Hsp70Bc)
   04131 Membrane trafficking [BR:dme04131]
    Dmel_CG6489 (Hsp70Bc)
   03051 Proteasome [BR:dme03051]
    Dmel_CG6489 (Hsp70Bc)
   03029 Mitochondrial biogenesis [BR:dme03029]
    Dmel_CG6489 (Hsp70Bc)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:dme04147]
    Dmel_CG6489 (Hsp70Bc)
Protein phosphatases and associated proteins [BR:dme01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-5
    PP5-interacting proteins
     Dmel_CG6489 (Hsp70Bc)
Spliceosome [BR:dme03041]
 Complex B
  Other components
   Prp19 complex
    Dmel_CG6489 (Hsp70Bc)
 Complex C
   Prp19-CDC5 complex
    Dmel_CG6489 (Hsp70Bc)
Ribosome biogenesis [BR:dme03009]
 Eukaryotic type
  Pre-60S particles
   Export and cytoplasmic maturation factors
    Dmel_CG6489 (Hsp70Bc)
Chaperones and folding catalysts [BR:dme03110]
 Heat shock proteins
  HSP70 / DNAK
   Dmel_CG6489 (Hsp70Bc)
Membrane trafficking [BR:dme04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Other core components
    Dmel_CG6489 (Hsp70Bc)
 Autophagy
  Chaperone mediated autophagy (CMA)
   Chaperones
    Dmel_CG6489 (Hsp70Bc)
Proteasome [BR:dme03051]
 Eukaryotic proteasome
  Assembling factors
   Other assembling factors
    Dmel_CG6489 (Hsp70Bc)
Mitochondrial biogenesis [BR:dme03029]
 Mitochondrial protein import machinery
  Endoplasmic reticulum membrane and cytosol
   Other ER-memrane and cytosol factors
    Dmel_CG6489 (Hsp70Bc)
Exosome [BR:dme04147]
 Exosomal proteins
  Proteins found in most exosomes
   Dmel_CG6489 (Hsp70Bc)
SSDB
Motif
Pfam: HSP70 MreB_Mbl Hydantoinase_A DUF4795 StbA Phage_lysozyme
Other DBs
NCBI-GeneID: 48583
NCBI-ProteinID: NP_650209
FlyBase: FBgn0013279
UniProt: Q8INI8 Q9BIS2 Q9BIR7
Position
3R
AA seq 641 aa
MPAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNP
RNTVFDAKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMV
LTKMKETAEAYLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAY
GLDKNLKGERNVLIFDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLA
EEFKRKYKKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARF
EELCADLFRNTLQPVEKALNDAKMDKGQIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLS
INPDEAVAYGAAVQAAILSGDQSGKIQDVLLVDVAPLSLGIETAGGVMTKLIERNCRIPC
KQTKTFSTYSDNQPGVSIQVYEGERAMTKDNNALGTFDLSGIPPAPRGVPQIEVTFDLDA
NGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAEKYADEDEKHRQRITSRNAL
ESYVFNVKQSVEQAPAGKLDEADKNSVLDKCNETIRWLDSNTTAEKEEFDHKMEELTRHC
SPIMTKMHQQGAGAAGGPGANCGQQAGGFGGYSGPTVEEVD
NT seq 1926 nt   +upstreamnt  +downstreamnt
atgcctgctattggaatcgatctgggcaccacctactcctgcgtgggtgtctaccagcat
ggcaaggttgagattatcgccaatgaccagggcaaccgcaccacgccgtcctacgtggct
ttcacagactcggaacgcctcattggtgatccggccaagaaccaggtggccatgaacccc
agaaacacagtgtttgacgccaagcgactcatcggccgaaaatacgacgatcccaaaatc
gcagaggacatgaagcactggcctttcaaagttgtaagcgacggcggaaagcccaagatc
ggggtggagtataagggtgagtccaagagatttgctcccgaggagatcagttcgatggtg
ctgaccaagatgaaggagacggcggaggcgtatctgggcgagagcatcacggatgcagtc
atcacagttccagcttacttcaacgactctcagcgccaggctaccaaagacgccggtcac
atcgccggcctgaatgtgctccgcatcatcaatgagcccacggcggcagcattggcctac
ggactggacaagaacctcaagggtgagcgcaatgtgcttatcttcgacttgggcggcggc
accttcgatgtctccatcctgaccatcgacgagggatctctgttcgaggtgcgctccaca
gccggagacacacacttgggcggcgaggactttgacaaccggctagtcacccacctggcg
gaggagttcaagcgcaagtacaagaaggatctgcgctccaaccctcgcgccctacgacgc
ctcagaacagcagctgaacgggccaagcgcacactctcctctagcacggaggccaccatc
gagatcgacgcattgtttgagggccaagacttctacaccaaagtaagccgtgccaggttt
gaggagctgtgcgcggacctcttccgcaacaccctgcagcctgtggagaaggccctcaac
gatgccaagatggacaagggtcagatccacgacatcgtactcgtcggcggatccactcgc
attcccaaggtgcaaagtctgctgcaggagttcttccacggcaagaacctcaacctatcc
atcaacccagacgaggcagtggcatacggagctgctgtgcaggccgctatcctcagcgga
gaccagagcggcaagatccaggacgtgctgctggtggacgtggccccactttcattggga
attgagaccgctggaggtgtaatgaccaagctgatcgagcgcaactgtcgcattccgtgc
aagcagactaagacgttctccacgtactcggacaaccagcccggagtctccatccaggtg
tatgagggcgaacgtgcgatgacgaaggacaacaatgcattgggcaccttcgatctgtcc
ggcattccacctgcaccaaggggtgtgccccagatagaagtaaccttcgacttggacgcc
aatggaatcctgaacgtcagcgccaaggagatgagcacgggcaaggccaagaacatcacg
atcaagaacgacaagggacgcctctcgcaggccgagattgatcgcatggtgaacgaggct
gagaagtacgccgacgaggacgaaaagcatcgccagcgcataacctctagaaatgctctg
gagagctacgtgttcaacgtaaagcagtccgtggagcaggcgcccgctggcaaactggac
gaggccgacaagaactccgtcctggacaagtgcaacgaaactattcgatggctggacagc
aacaccaccgccgagaaggaggagttcgaccacaagatggaggagctcactcgccactgc
tcccctatcatgaccaagatgcatcagcagggagcgggagcagctgggggtccgggagcc
aactgtggccaacaggccggaggatttggcggctactctggacccacagtcgaggaggtc
gactaa

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