KEGG   Drosophila melanogaster (fruit fly): Dmel_CG6502
Entry
Dmel_CG6502       CDS       T00030                                 
Symbol
E(z)
Name
(RefSeq) enhancer of zeste, isoform B
  KO
K11430  [histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:2.1.1.356]
Organism
dme  Drosophila melanogaster (fruit fly)
Pathway
dme00310  Lysine degradation
dme01100  Metabolic pathways
dme03083  Polycomb repressive complex
Brite
KEGG Orthology (KO) [BR:dme00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    Dmel_CG6502 (E(z))
 09120 Genetic Information Processing
  09126 Chromosome
   03083 Polycomb repressive complex
    Dmel_CG6502 (E(z))
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:dme03036]
    Dmel_CG6502 (E(z))
Enzymes [BR:dme01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.356  [histone H3]-lysine27 N-trimethyltransferase
     Dmel_CG6502 (E(z))
Chromosome and associated proteins [BR:dme03036]
 Eukaryotic type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     Dmel_CG6502 (E(z))
   Polycomb repressive complex (PRC) and associated proteins
    PRC2.1
     Dmel_CG6502 (E(z))
    PRC2.2
     Dmel_CG6502 (E(z))
SSDB
Motif
Pfam: Ezh2_MCSS PRC2_HTH_1 SET preSET_CXC Latrophilin
Other DBs
NCBI-GeneID: 39203
NCBI-ProteinID: NP_001137932
FlyBase: FBgn0000629
UniProt: P42124
Position
3L:complement(10634575..10638130)
AA seq 760 aa
MNSTKVPPEWKRRVKSEYIKIRQQKRYKRADEIKEAWIRNWDEHNHNVQDLYCESKVWQA
KPYDPPHVDCVKRAEVTSYNGIPSGPQKVPICVINAVTPIPTMYTWAPTQQNFMVEDETV
LHNIPYMGDEVLDKDGKFIEELIKNYDGKVHGDKDPSFMDDAIFVELVHALMRSYSKELE
EAAPGTATAIKTETLAKSKQGEDDGVVDVDADGESPMKLEKTDSKGDLTEVEKKETEEPL
ETEDADVKPDVEEVKDKLPFPAPIIFQAISANFPDKGTAQELKEKYIELTEHQDPERPQE
CTPNIDGIKAESVSRERTMHSFHTLFCRRCFKYDCFLHRLQGHAGPNLQKRRYPELKPFA
EPCSNSCYMLIDGMKEKLAADSKTPPIDSCNEASSEDSNDSNSQFSNKDFNHENSKDNGL
TVNSAAVAEINSIMAGMMNITSTQCVWTGADQALYRVLHKVYLKNYCAIAHNMLTKTCRQ
VYEFAQKEDAEFSFEDLRQDFTPPRKKKKKQRLWSLHCRKIQLKKDSSSNHVYNYTPCDH
PGHPCDMNCSCIQTQNFCEKFCNCSSDCQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLC
QACGADQFKLTKITCKNVCVQRGLHKHLLMAPSDIAGWGIFLKEGAQKNEFISEYCGEII
SQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSINPNCYAKVMMVTGDH
RIGIFAKRAIQPGEELFFDYRYGPTEQLKFVGIEREMEIV
NT seq 2283 nt   +upstreamnt  +downstreamnt
atgaatagcactaaagtgccgcccgagtggaagaggcgtgtcaagtcggagtacatcaaa
atcaggcagcagaagcgctacaaacgtgccgacgagatcaaggaggcgtggataagaaac
tgggacgagcacaaccacaatgtacaggatctgtactgcgagtcgaaggtttggcaggct
aaaccctacgatccgccgcatgtggactgtgtgaagcgggcggaggtgactagctacaat
ggcattcccagcggtccgcaaaaggtgcccatttgcgtgatcaacgcggtcactcccata
cccaccatgtacacgtgggcaccaacacagcagaacttcatggtggaggatgagacggtg
ctgcacaatataccctatatgggcgacgaggtcctcgataaggatggcaagttcatagag
gaactgatcaaaaactacgatggcaaggttcacggcgacaaggatccctcgttcatggac
gatgccatcttcgtagaactggtgcacgcccttatgcgctcctacagcaaggaactggag
gaagccgctccgggtacagcgactgccattaaaacagagacgttggcgaaatcaaaacag
ggcgaagatgatggggtagttgatgttgacgcagatggtgaatctcccatgaagcttgag
aaaaccgacagcaaaggggatctgactgaagttgagaagaaggaaactgaagaaccgctg
gagactgaagatgcggatgttaagcccgatgtggaagaagtcaaggacaagctgcccttc
cctgcgcccattatttttcaggccatcagcgctaactttccagacaagggcaccgcgcaa
gagctcaaagaaaagtacattgagcttacggagcaccaggatccggagcgcccacaggag
tgcacacccaacattgacggcatcaaggccgagagcgtttcccgggaaaggactatgcac
tcctttcacacgctcttctgtcgtcgttgcttcaaatacgactgcttcctgcaccgcttg
caaggacatgcgggtcccaatctccagaagcgtcgctatccggaactgaagcctttcgcc
gaaccttgcagcaactcctgctacatgttgatcgatggcatgaaggaaaagctggcggcc
gatagcaagacacctcccattgattcctgcaatgaggccagctccgaggacagtaatgac
agcaacagtcagtttagcaacaaggactttaatcatgagaatagcaaggataatggcctg
actgtaaatagcgccgctgtggctgagatcaactccattatggctggcatgatgaacatc
accagtacgcagtgcgtttggacaggcgctgaccaagcactttatcgggtcttgcataaa
gtgtatttaaagaactactgcgcgattgcgcacaacatgctgaccaagacctgtcgtcag
gtgtacgagtttgcccagaaggaggatgctgagtttagcttcgaggatttgcgacaggac
ttcacacctccgcgcaagaagaagaagaagcaacgtctgtggtcgctgcactgtcgtaag
attcagctaaagaaggactcatcctcgaatcacgtgtacaactacacgccctgcgaccat
cccggacatccatgcgacatgaactgctcctgcattcagacacaaaacttctgcgaaaag
ttctgcaactgcagcagcgattgccagaatcgtttccccggctgtcgctgcaaggctcag
tgcaatacgaagcagtgtccttgctatctggcagtgcgcgagtgtgatcccgatctgtgc
caggcctgcggagcggatcagtttaagctgaccaagatcacgtgcaagaacgtgtgcgtg
cagcgaggactgcacaagcacctgctcatggctccgtctgacatcgccggctggggcatc
tttcttaaggagggtgcgcaaaagaatgagttcatttcggaatattgtggcgagatcata
tcccaagatgaagccgatcgccgtggcaaggtttacgacaagtacatgtgctcatttctt
ttcaatctgaacaacgattttgttgtggatgccactcggaagggcaacaagattcggttt
gccaatcattccattaatcccaattgctatgccaaggttatgatggtcaccggcgatcat
cgcatcggcatctttgccaagcgggccattcagcccggcgaagagctattctttgactac
agatacggacccacggagcagctgaagttcgtgggcatagagcgtgaaatggaaattgtt
tga

  All links  
Gene (57)   
   RefGene (53)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   FLYBASE (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (5)   
   Pfam (5)   
All databases (70)   

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