KEGG   Drosophila melanogaster (fruit fly): Dmel_CG7756
Entry
Dmel_CG7756       CDS       T00030                                 
Symbol
Hsc70-2
Name
(RefSeq) heat shock protein 70 cognate 2
  KO
K03283  heat shock 70kDa protein 1/6/8
Organism
dme  Drosophila melanogaster (fruit fly)
Pathway
dme03040  Spliceosome
dme04141  Protein processing in endoplasmic reticulum
dme04144  Endocytosis
dme04213  Longevity regulating pathway - multiple species
Brite
KEGG Orthology (KO) [BR:dme00001]
 09120 Genetic Information Processing
  09121 Transcription
   03040 Spliceosome
    Dmel_CG7756 (Hsc70-2)
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    Dmel_CG7756 (Hsc70-2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    Dmel_CG7756 (Hsc70-2)
 09150 Organismal Systems
  09149 Aging
   04213 Longevity regulating pathway - multiple species
    Dmel_CG7756 (Hsc70-2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:dme01009]
    Dmel_CG7756 (Hsc70-2)
  09182 Protein families: genetic information processing
   03041 Spliceosome [BR:dme03041]
    Dmel_CG7756 (Hsc70-2)
   03009 Ribosome biogenesis [BR:dme03009]
    Dmel_CG7756 (Hsc70-2)
   03110 Chaperones and folding catalysts [BR:dme03110]
    Dmel_CG7756 (Hsc70-2)
   04131 Membrane trafficking [BR:dme04131]
    Dmel_CG7756 (Hsc70-2)
   03051 Proteasome [BR:dme03051]
    Dmel_CG7756 (Hsc70-2)
   03029 Mitochondrial biogenesis [BR:dme03029]
    Dmel_CG7756 (Hsc70-2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:dme04147]
    Dmel_CG7756 (Hsc70-2)
Protein phosphatases and associated proteins [BR:dme01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-5
    PP5-interacting proteins
     Dmel_CG7756 (Hsc70-2)
Spliceosome [BR:dme03041]
 Complex B
  Other components
   Prp19 complex
    Dmel_CG7756 (Hsc70-2)
 Complex C
   Prp19-CDC5 complex
    Dmel_CG7756 (Hsc70-2)
Ribosome biogenesis [BR:dme03009]
 Eukaryotic type
  Pre-60S particles
   Export and cytoplasmic maturation factors
    Dmel_CG7756 (Hsc70-2)
Chaperones and folding catalysts [BR:dme03110]
 Heat shock proteins
  HSP70 / DNAK
   Dmel_CG7756 (Hsc70-2)
Membrane trafficking [BR:dme04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Other core components
    Dmel_CG7756 (Hsc70-2)
 Autophagy
  Chaperone mediated autophagy (CMA)
   Chaperones
    Dmel_CG7756 (Hsc70-2)
Proteasome [BR:dme03051]
 Eukaryotic proteasome
  Assembling factors
   Other assembling factors
    Dmel_CG7756 (Hsc70-2)
Mitochondrial biogenesis [BR:dme03029]
 Mitochondrial protein import machinery
  Endoplasmic reticulum membrane and cytosol
   Other ER-memrane and cytosol factors
    Dmel_CG7756 (Hsc70-2)
Exosome [BR:dme04147]
 Exosomal proteins
  Proteins found in most exosomes
   Dmel_CG7756 (Hsc70-2)
SSDB
Motif
Pfam: HSP70 MreB_Mbl FGGY_C Hydantoinase_A
Other DBs
NCBI-GeneID: 41609
NCBI-ProteinID: NP_524339
FlyBase: FBgn0001217
UniProt: P11146
Structure
Position
3R
AA seq 633 aa
MGKIPAIGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAFNETERLIGDPAKNQVA
MNAKNTVFDAKRLIGRKFDDKKIQEDLKLWPFKVINEKGKPKIEVEFKGERKRFAPEEIS
SMVLTKMREIAEVYLGGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAA
LAYGLDKNLKGERNVLIFDLGGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVN
HFAEEFKRKHKSDIKGNARALRRLRTACERAKRTLSSSTEASLEIDALHEGIDFYSKISR
ARFEELNMDLFRSTMQPVERALSDAKMDKKAIHDVVLVGGSTRIPKIQKLLQDLFGGKQL
NLSINPDEAVAYGAAVQAAILTGVGSSQIQDLLLVDVAPLSLGIETAGGVMTNLVERNAR
IPCKQQQIFTTYSDNQNAVTIQVYEGERAMTKDNNLLGTFNLTGIPPAPRGVPQIEVAFD
LNADGILNVNAKDNSTGKSEKITISNDKGRLSKAEIDRMLSEAEKYKVEDDRQRERVQSK
NNLEAYIYACRQAVDDAPSGVLSETERSKVRDKCSSEASWLDKNSLAEKEEFESHLKECQ
RICTPIMSKIHGGKKGKSSMGKGSHPTVEEVDG
NT seq 1902 nt   +upstreamnt  +downstreamnt
atgggtaaaattccggccatcggcatcgacttgggcaccacctactcctgtgtgggagtt
tggcagaacagcaaggtggagatcatcgccaacgatcagggaaaccgcaccacgccctcg
tatgtggcattcaacgagacggagcgcttgattggcgatccggccaagaaccaggtggcc
atgaatgccaagaacacggttttcgatgccaagcgattgattggacggaagttcgacgac
aagaagatacaggaggacctgaagctctggcccttcaaggtcatcaatgagaagggaaag
ccgaagatcgaggtggagttcaagggcgaacggaagcgatttgcccccgaggagatcagt
tcgatggtgctgaccaagatgcgcgaaatcgccgaggtctatctgggtggcaaggtgaag
gacgcggtggtcacagtgccggcctacttcaatgatagccagcgtcaggcgaccaaggat
gcgggctccattgctggactgaatgtgctgaggatcatcaatgagcccactgcggcagct
ctggcctatgggctggataagaatcttaagggagagcgaaatgtgctcatcttcgacttg
ggcggcggcaccttcgacgtctccgtactgagcatcgatgagggttccctgttcgaggtg
aaggccacggccggcgatacccatttgggtggtgaggatttcgacaaccggttggtcaat
cattttgccgaggaattcaagcggaagcacaagtcggacatcaagggaaatgccagagcg
ttgagacgcctgagaacggcttgtgaacgggcgaagaggacgttgtcctccagcacggag
gcatccttggagattgatgccctgcacgagggcattgacttttactcgaaaatttcgaga
gcgcgtttcgaggagctgaacatggacctcttccggtccaccatgcagccggtggagcgg
gcactgagcgatgccaagatggacaagaaggccattcatgatgtggtcctggtgggcggc
tccacgcgtattcccaagattcagaaactactgcaagatctgtttggtggcaagcagcta
aatctttcaatcaatcccgatgaggcggtggcttatggagccgccgtacaggctgccatt
ctcaccggcgtgggcagctcacagatccaggacctgctcctcgtggacgtggctcccctt
tcgctgggcatcgagaccgctggcggcgtgatgaccaacttggtggagcgcaatgcccgc
attccctgcaagcagcagcagatcttcaccacctacagtgacaaccagaatgcggtgacc
attcaggtgtacgagggcgagcgggccatgaccaaggataacaatctactgggcaccttt
aacctcaccggcattccgccagctcctcggggagtgccccagatcgaggtggccttcgac
ttgaatgcggatggcatcctgaatgtgaatgccaaggacaacagcaccgggaagagcgaa
aagatcaccatttccaacgacaagggcagactttccaaagcggaaatcgatcgcatgctc
tcggaggcggagaagtacaaggtcgaggacgatcgtcagagggagcgggttcagtccaag
aacaatctcgaggcatacatctacgcatgtcgccaggccgtcgacgacgctccatccggc
gttctttccgaaaccgaacgctccaaggtgcgcgacaagtgctcctccgaggcatcctgg
ctggacaagaactcgctggccgagaaggaggagttcgagagtcacctgaaagagtgccag
cgcatctgtactccaataatgtcgaaaatccatggcggcaaaaagggcaaatcatcgatg
ggcaagggttcccatcccactgtggaggaggtggatggatag

  All links  
Gene (27)   
   RefGene (23)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   FLYBASE (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
3D Structure (1)   
   PDB (1)   
Protein domain (4)   
   Pfam (4)   
All databases (36)   

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