KEGG   DRUG: Nalidixic acid
Entry
D00183                      Drug                                   

Name
Nalidixic acid (JP17/USP/INN);
NegGram (TN)
Formula
C12H12N2O3
Exact mass
232.0848
Mol weight
232.2353
Structure
Simcomp
Class
Antibacterial
 DG01550  Quinolone
Other
 DG01529  Topoisomerase inhibitor
  DG01528  Topoisomerase IV inhibitor
Remark
Same as: C05079
ATC code: J01MB02
Chemical structure group: DG00630
Efficacy
Antibacterial, Nucleic acid biosynthesis inhibitor
Target
DNA gyrase [KO:K02469 K02470]
Interaction
Structure map
map07014  Quinolones
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01M QUINOLONE ANTIBACTERIALS
    J01MB Other quinolones
     J01MB02 Nalidixic acid
      D00183  Nalidixic acid (JP17/USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00183  Nalidixic acid
Pharmacogenomic biomarkers [br08341.html]
 Polymorphisms and mutations affecting drug response
  D00183
Other DBs
CAS: 389-08-2
PubChem: 7847251
ChEBI: 100147
ChEMBL: CHEMBL5
DrugBank: DB00779
PDB-CCD: NIX[PDBj]
LigandBox: D00183
NIKKAJI: J2.039G
KCF data

ATOM        17
            1   C8y C    24.4685  -17.3910
            2   C8y C    24.4685  -15.9905
            3   N4y N    25.6963  -18.1008
            4   N5x N    23.2472  -18.1071
            5   C8y C    25.6836  -15.2743
            6   C8x C    23.2472  -15.2936
            7   C8x C    26.8773  -17.3975
            8   C1b C    25.6899  -19.4883
            9   C8y C    22.0386  -17.3910
            10  C8y C    26.9113  -15.9776
            11  O5x O    25.6770  -13.8803
            12  C8x C    22.0386  -15.9905
            13  C1a C    24.4878  -20.1854
            14  C1a C    20.8301  -18.0816
            15  C6a C    28.1134  -15.2807
            16  O6a O    29.3221  -15.9713
            17  O6a O    28.1706  -13.8868
BOND        18
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     3   8 1
            8     4   9 2
            9     5  10 1
            10    5  11 2
            11    6  12 2
            12    8  13 1
            13    9  14 1
            14   10  15 1
            15   15  16 1
            16   15  17 2
            17    7  10 2
            18    9  12 1

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