KEGG   DRUG: Stavudine
Entry
D00445                      Drug                                   
Name
Stavudine (USAN/INN);
Sanilvudine (JAN);
Zerit (TN)
  Abbr
d4T
Product
  Generic
Formula
C10H12N2O4
Exact mass
224.0797
Mol weight
224.2133
Structure
Simcomp
Class
Antiviral
 DG01890  Nucleoside reverse transcriptase inhibitor (NRTI)
 DG03107  Anti-HIV agent
  DG01656  HIV reverse transcriptase inhibitor
Remark
Same as: C07312
ATC code: J05AF04
Product: D00445<US>
Efficacy
Antiviral, Reverse transcriptase inhibitor
  Disease
HIV-1 infection [DS:H01563]
Target
HIV-1 reverse transcriptase [KO:K24802]
Interaction
Structure map
map07044  Antiviral agents
map07053  Anti-HIV agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J05 ANTIVIRALS FOR SYSTEMIC USE
   J05A DIRECT ACTING ANTIVIRALS
    J05AF Nucleoside and nucleotide reverse transcriptase inhibitors
     J05AF04 Stavudine
      D00445  Stavudine (USAN/INN) <US>
USP drug classification [BR:br08302]
 Antivirals
  Anti-HIV Agents, Nucleoside and Nucleotide Reverse Transcriptase Inhibitors (NRTI)
   Stavudine
    D00445  Stavudine (USAN/INN)
Drug groups [BR:br08330]
 Antiviral
  DG01890  Nucleoside reverse transcriptase inhibitor (NRTI)
   D00445  Stavudine
  DG03107  Anti-HIV agent
   DG01656  HIV reverse transcriptase inhibitor
    D00445  Stavudine
Drug classes [BR:br08332]
 Antiviral
  DG03107  Anti-HIV agent
   D00445  Stavudine
Antimicrobials [BR:br08307]
 Antivirals
  Genome replication inhibitor
   HIV reverse transcriptase inhibitor
    D00445  Stavudine (USAN/INN) <US>
Antimicrobials abbreviations [BR:br08327]
 Antivirals
  Genome replication inhibitor
   HIV reverse transcriptase inhibitor
    D00445  Stavudine (USAN/INN)
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D00445
Other DBs
CAS: 3056-17-5
PubChem: 7847511
ChEBI: 63581
LigandBox: D00445
NIKKAJI: J83.276F
KCF data

ATOM        16
            1   C1y C    23.3375  -17.1684
            2   N4y N    24.7304  -16.2773
            3   O2x O    22.2047  -16.3383
            4   C2x C    22.8796  -18.5037
            5   C8y C    25.9417  -15.5769
            6   C8x C    23.5292  -15.5678
            7   C1y C    21.0616  -17.1462
            8   C2x C    21.4815  -18.4900
            9   N4x N    25.9604  -14.1782
            10  O5x O    27.1422  -16.2880
            11  C8y C    23.5311  -14.1636
            12  C1b C    19.7320  -16.7119
            13  C8y C    24.7525  -13.4704
            14  C1a C    22.3517  -13.3997
            15  O1a O    18.6814  -17.6318
            16  O5x O    24.7621  -12.0810
BOND        17
            1     1   2 1 #Up
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     4   8 2
            8     5   9 1
            9     5  10 2
            10    6  11 2
            11    7  12 1 #Up
            12    9  13 1
            13   11  14 1
            14   12  15 1
            15   13  16 2
            16    7   8 1
            17   11  13 1

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