KEGG   DRUG: Stavudine
Entry
D00445                      Drug                                   

Name
Stavudine (USAN/INN);
Sanilvudine (JAN);
Zerit (TN)
  Abbr
d4T
Product
  Generic
Formula
C10H12N2O4
Exact mass
224.0797
Mol weight
224.2133
Structure
Simcomp
Class
Antiviral
 DG01890  Nucleoside reverse transcriptase inhibitor (NRTI)
 DG01656  HIV reverse transcriptase inhibitor
Remark
Same as: C07312
ATC code: J05AF04
Product: D00445<US>
Efficacy
Antiviral, Reverse transcriptase inhibitor
  Disease
HIV-1 infection [DS:H01563]
Target
HIV-1 reverse transcriptase [KO:K24802]
Interaction
Structure map
map07044  Antiviral agents
map07053  Anti-HIV agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J05 ANTIVIRALS FOR SYSTEMIC USE
   J05A DIRECT ACTING ANTIVIRALS
    J05AF Nucleoside and nucleotide reverse transcriptase inhibitors
     J05AF04 Stavudine
      D00445  Stavudine (USAN/INN) <US>
USP drug classification [BR:br08302]
 Antivirals
  Anti-HIV Agents, Nucleoside and Nucleotide Reverse Transcriptase Inhibitors (NRTI)
   Stavudine
    D00445  Stavudine (USAN/INN)
Antiinfectives [BR:br08307]
 Antivirals
  Genome replication inhibitor
   HIV reverse transcriptase inhibitor
    D00445  Stavudine (USAN/INN) <US>
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D00445
Other DBs
CAS: 3056-17-5
PubChem: 7847511
ChEBI: 63581
ChEMBL: CHEMBL991
DrugBank: DB00649
LigandBox: D00445
NIKKAJI: J83.276F
KCF data

ATOM        16
            1   C1y C    23.3375  -17.1684
            2   N4y N    24.7304  -16.2773
            3   O2x O    22.2047  -16.3383
            4   C2x C    22.8796  -18.5037
            5   C8y C    25.9417  -15.5769
            6   C8x C    23.5292  -15.5678
            7   C1y C    21.0616  -17.1462
            8   C2x C    21.4815  -18.4900
            9   N4x N    25.9604  -14.1782
            10  O5x O    27.1422  -16.2880
            11  C8y C    23.5311  -14.1636
            12  C1b C    19.7320  -16.7119
            13  C8y C    24.7525  -13.4704
            14  C1a C    22.3517  -13.3997
            15  O1a O    18.6814  -17.6318
            16  O5x O    24.7621  -12.0810
BOND        17
            1     1   2 1 #Up
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     4   8 2
            8     5   9 1
            9     5  10 2
            10    6  11 2
            11    7  12 1 #Up
            12    9  13 1
            13   11  14 1
            14   12  15 1
            15   13  16 2
            16    7   8 1
            17   11  13 1

» Japanese version   » Back

DBGET integrated database retrieval system