| Entry |
|
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| Name |
Propantheline bromide (JP18/USP/INN);
Pro-banthine (TN) |
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| Formula |
C23H30NO3. Br
|
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| Exact mass |
447.1409
|
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| Mol weight |
448.3932
|
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| Structure |
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| Simcomp |
|
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| Class |
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
Gastrointestinal agent
DG01975 Agents for peptic ulcer
|
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| Remark |
| Therapeutic category: | 1231 |
| Product (DG00035): | D00481<JP> |
|
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| Efficacy |
Antispasmodic, Muscarinic acetylcholine receptor antagonist |
|---|
| Disease |
|
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| Comment |
Quaternary ammonium compound
|
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| Target |
|
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
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| Interaction |
|
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| Structure map |
| map07220 | Cholinergic and anticholinergic drugs |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
A03A DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
A03AB Synthetic anticholinergics, quaternary ammonium compounds
A03AB05 Propantheline
D00481 Propantheline bromide (JP18/USP/INN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
12 Agents affecting peripheral nervous system
123 Autonomic nervous system agents
1231 Quaternary ammoniums
D00481 Propantheline bromide (JP18/USP/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG00035 Propantheline
D00481 Propantheline bromide
Gastrointestinal agent
DG01975 Agents for peptic ulcer
DG00035 Propantheline
D00481 Propantheline bromide
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Acetylcholine (muscarinic)
CHRM
D00481 Propantheline bromide (JP18/USP/INN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00481 Propantheline bromide
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG00035 Propantheline
Gastrointestinal agent
DG01975 Agents for peptic ulcer
DG00035 Propantheline
|
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| Other DBs |
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| KCF data |
ATOM 28
1 X Br 29.5355 -11.2850 #-
2 C8x C 19.5645 -9.5721
3 C8x C 19.5645 -10.9775
4 C8x C 20.7816 -11.6802
5 C8y C 21.9987 -10.9775
6 C8y C 21.9987 -9.5721
7 C8x C 20.7816 -8.8695
8 O2x O 23.2157 -11.6802
9 C8y C 24.4328 -10.9775
10 C8y C 24.4328 -9.5721
11 C1y C 23.2157 -8.8695
12 C8x C 25.6499 -11.6802
13 C8x C 26.8669 -10.9775
14 C8x C 26.8669 -9.5721
15 C8x C 25.6499 -8.8695
16 C7a C 23.2157 -7.4641
17 O7a O 24.4349 -6.7602
18 O6a O 22.0007 -6.7626
19 C1b C 25.6359 -7.4539
20 C1b C 26.8273 -6.7661
21 N1d N 28.0233 -7.4569 #+
22 C1a C 28.0233 -8.8692
23 C1c C 28.0233 -6.0515
24 C1a C 29.2172 -5.3621
25 C1c C 29.4233 -7.4569
26 C1a C 26.7796 -5.3340
27 C1a C 30.1320 -8.6834
28 C1a C 30.1029 -6.2792
BOND 29
1 2 3 2
2 3 4 1
3 4 5 2
4 5 6 1
5 6 7 2
6 2 7 1
7 5 8 1
8 8 9 1
9 9 10 1
10 10 11 1
11 6 11 1
12 9 12 2
13 12 13 1
14 13 14 2
15 14 15 1
16 10 15 2
17 11 16 1
18 16 17 1
19 16 18 2
20 17 19 1
21 19 20 1
22 20 21 1
23 21 22 1
24 21 23 1
25 23 24 1
26 21 25 1
27 23 26 1
28 25 27 1
29 25 28 1
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