KEGG   DRUG: Trimetaphan camsilateHelp
Entry
D00612                      Drug                                   

Name
Trimetaphan camsilate (JAN/INN);
Trimetaphan camsylate;
Arfonad (TN)
Formula
C22H25N2OS. C10H15O4S
Exact mass
596.2379
Mol weight
596.8004
Structure
Mol fileKCF fileDB search
Class
Cardiovascular agent
 DG01695  Ganglion-blocking antiadrenergic
Remark
ATC code: C02BA01
Chemical structure group: DG00251
Efficacy
Antihypertensive
Comment
Sulfonium derivative
Target
CHRNA10 [HSA:57053] [KO:K04811]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C02 ANTIHYPERTENSIVES
   C02B ANTIADRENERGIC AGENTS, GANGLION-BLOCKING
    C02BA Sulfonium derivatives
     C02BA01 Trimetaphan
      D00612  Trimetaphan camsilate (JAN/INN)
Target-based classification of drugs [BR:br08310]
 Ion channels
  Ligand-gated ion channels
   Acetylcholine (nicotinic)
    CHRNA10
     D00612  Trimetaphan camsilate (JAN/INN)
BRITE hierarchy
Other DBs
CAS: 68-91-7
PubChem: 7847678
ChEBI: 9729
ChEMBL: CHEMBL1245
DrugBank: DB01116
LigandBox: D00612
NIKKAJI: J215.239H
KCF data Show

ATOM        41
            1   C1y C    19.2886  -16.3960
            2   C1y C    20.0479  -15.2220
            3   C1y C    17.9334  -16.0339
            4   N1y N    20.1647  -17.4826
            5   N1y N    21.4673  -15.5899
            6   C1x C    19.1660  -14.1355
            7   S2x S    17.9333  -14.6262 #+
            8   C1x C    16.6191  -16.5304
            9   C5x C    21.4674  -16.9861
            10  C1b C    20.1473  -18.8785
            11  C1b C    22.6122  -14.8949
            12  C1x C    16.5081  -14.2581
            13  C1x C    15.7371  -15.4381
            14  O5x O    22.6415  -17.7453
            15  C8y C    21.3505  -19.5912
            16  C8y C    23.8213  -15.5958
            17  C8x C    21.3331  -20.9814
            18  C8x C    22.5654  -18.8960
            19  C8x C    23.8213  -16.9918
            20  C8x C    25.0305  -14.9006
            21  C8x C    22.5363  -21.6941
            22  C8x C    23.7688  -19.6086
            23  C8x C    25.0305  -17.6928
            24  C8x C    26.2396  -15.5958
            25  C8x C    23.7571  -21.0048
            26  C8x C    26.2396  -16.9918
            27  C1z C    32.5073  -18.2243
            28  C1z C    31.9115  -16.1157
            29  C5x C    33.6463  -18.7910
            30  C1x C    31.2864  -18.8318
            31  C1b C    31.8707  -19.5211
            32  C1y C    32.8520  -17.0853
            33  C1a C    32.4197  -14.7488
            34  C1a C    30.8543  -15.3212
            35  C1x C    34.1137  -17.8097
            36  O5x O    34.0961  -20.1285
            37  C1x C    31.8590  -17.7920
            38  S4a S    30.4921  -19.5270
            39  O1d O    29.8671  -20.7653
            40  O1d O    29.7385  -18.3761
            41  O1d O    31.5260  -20.6601 #-
BOND        46
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     3   8 1
            8     4   9 1
            9     4  10 1
            10    5  11 1
            11    7  12 1
            12    8  13 1
            13    9  14 2
            14   10  15 1
            15   11  16 1
            16   15  17 2
            17   15  18 1
            18   16  19 2
            19   16  20 1
            20   17  21 1
            21   18  22 2
            22   19  23 1
            23   20  24 2
            24   21  25 2
            25   23  26 2
            26    5   9 1
            27    6   7 1
            28   12  13 1
            29   22  25 1
            30   24  26 1
            31   27  28 1
            32   27  29 1
            33   27  30 1
            34   27  31 1
            35   28  32 1
            36   28  33 1
            37   28  34 1
            38   29  35 1
            39   29  36 2
            40   30  37 1
            41   31  38 1
            42   38  39 2
            43   38  40 2
            44   38  41 1
            45   32  35 1
            46   32  37 1

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