| Entry |
|
|---|
| Name |
Methazolamide (JAN/USP/INN);
Neptazane (TN) |
|---|
| Product |
|
|---|
| Generic |
METHAZOLAMIDE (ANI Pharmaceuticals), METHAZOLAMIDE (Bausch & Lomb Incorporated), METHAZOLAMIDE (Bryant Ranch Prepack), METHAZOLAMIDE (Bryant Ranch Prepack), METHAZOLAMIDE (Bryant Ranch Prepack), METHAZOLAMIDE (Bryant Ranch Prepack), METHAZOLAMIDE (Coupler LLC), METHAZOLAMIDE (Golden State Medical Supply), METHAZOLAMIDE (Micro Labs Limited), METHAZOLAMIDE (NorthStar Rx LLC), METHAZOLAMIDE (Oceanside Pharmaceuticals), METHAZOLAMIDE (Padagis US LLC), METHAZOLAMIDE (Precision Dose) |
|---|
| Formula |
C5H8N4O3S2
|
|---|
| Exact mass |
236.0038
|
|---|
| Mol weight |
236.28
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01534 Carbonic anhydrase inhibitor
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
|
|---|
| Remark |
|
|---|
| Efficacy |
Antiglaucoma, Carbonic anhydrase inhibitor |
|---|
| Disease |
Open-angle glaucoma [DS: H00612] |
|---|
| Target |
|
|---|
| Pathway |
| hsa04964 | Proximal tubule bicarbonate reclamation |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07017 | Sulfonamide derivatives - diuretics |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
S01EC Carbonic anhydrase inhibitors
S01EC05 Methazolamide
D00655 Methazolamide (JAN/USP/INN) <US>
USP drug classification [BR:br08302]
Ophthalmic Agents
Intraocular Pressure Lowering Agents
Carbonic Anhydrase Inhibitors, Ophthalmic
Methazolamide
D00655 Methazolamide (JAN/USP/INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01534 Carbonic anhydrase inhibitor
D00655 Methazolamide
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
D00655 Methazolamide
Drug classes [BR:br08332]
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
D00655 Methazolamide
Target-based classification of drugs [BR:br08310]
Enzymes
Lyases (EC4)
Aldehyde-lyases
CA
D00655 Methazolamide (JAN/USP/INN) <US>
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 14
1 C8y C 26.4566 -18.5315
2 S2x S 25.3215 -17.7066
3 N4y N 26.0236 -19.8597
4 N2b N 27.6618 -17.8177
5 C8y C 24.1866 -18.5315
6 N5x N 24.6254 -19.8597
7 C1a C 26.8486 -20.9889
8 C5a C 28.8729 -18.5198
9 S4a S 22.7882 -18.5258
10 C1a C 30.0841 -17.8120
11 O5a O 28.8729 -19.9183
12 N1a N 22.8465 -19.9240
13 O3c O 22.8465 -17.1273
14 O3c O 21.3840 -18.5258
BOND 14
1 1 2 1
2 1 3 1
3 1 4 2
4 2 5 1
5 3 6 1
6 3 7 1
7 4 8 1
8 5 9 1
9 8 10 1
10 8 11 2
11 9 12 1
12 9 13 2
13 9 14 2
14 5 6 2
|
|---|
