| Entry |
|
|---|
| Name |
Methazolamide (JAN/USP/INN);
Neptazane (TN)
|
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C5H8N4O3S2
|
|---|
| Exact mass |
236.0038
|
|---|
| Mol weight |
236.272
|
|---|
| Structure |
   |
|---|
| Simcomp |
 |
|---|
| Class |
Cardiovascular agent
DG01534 Carbonic anhydrase inhibitor
|
|---|
| Remark |
|
|---|
| Efficacy |
Antiglaucoma, Carbonic anhydrase inhibitor |
|---|
| Disease |
Open-angle glaucoma [DS: H00612] |
|---|
| Target |
|
|---|
| Pathway |
| hsa04964 | Proximal tubule bicarbonate reclamation |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07017 | Sulfonamide derivatives - diuretics |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
S01EC Carbonic anhydrase inhibitors
S01EC05 Methazolamide
D00655 Methazolamide (JAN/USP/INN) <US>
USP drug classification [BR:br08302]
Cardiovascular Agents
Diuretics, Carbonic Anhydrase Inhibitors
Methazolamide
D00655 Methazolamide (JAN/USP/INN)
Ophthalmic Agents
Ophthalmic Antiglaucoma Agents
Methazolamide
D00655 Methazolamide (JAN/USP/INN)
Target-based classification of drugs [BR:br08310]
Enzymes
Lyases (EC4)
Aldehyde-lyases
CA
D00655 Methazolamide (JAN/USP/INN) <US>
 |
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 14
1 C8y C 26.4566 -18.5315
2 S2x S 25.3215 -17.7066
3 N4y N 26.0236 -19.8597
4 N2b N 27.6618 -17.8177
5 C8y C 24.1866 -18.5315
6 N5x N 24.6254 -19.8597
7 C1a C 26.8486 -20.9889
8 C5a C 28.8729 -18.5198
9 S4a S 22.7882 -18.5258
10 C1a C 30.0841 -17.8120
11 O5a O 28.8729 -19.9183
12 N1a N 22.8465 -19.9240
13 O3c O 22.8465 -17.1273
14 O3c O 21.3840 -18.5258
BOND 14
1 1 2 1
2 1 3 1
3 1 4 2
4 2 5 1
5 3 6 1
6 3 7 1
7 4 8 1
8 5 9 1
9 8 10 1
10 8 11 2
11 9 12 1
12 9 13 2
13 9 14 2
14 5 6 2
|
|---|
