KEGG   DRUG: Trihexyphenidyl hydrochlorideHelp
Entry
D00787                      Drug                                   

Name
Trihexyphenidyl hydrochloride (JP17/USP);
Artane (TN)
Product
  Generic
TRIHEXYPHENIDYL HYDROCHLORIDE (A-S Medication Solutions), TRIHEXYPHENIDYL HYDROCHLORIDE (A-S Medication Solutions), TRIHEXYPHENIDYL HYDROCHLORIDE (Actavis Pharma), TRIHEXYPHENIDYL HYDROCHLORIDE (Bionpharma), TRIHEXYPHENIDYL HYDROCHLORIDE (Golden State Medical Supply), TRIHEXYPHENIDYL HYDROCHLORIDE (Mikart), TRIHEXYPHENIDYL HYDROCHLORIDE (Natco Pharma Limited), TRIHEXYPHENIDYL HYDROCHLORIDE (Novitium Pharma LLC), TRIHEXYPHENIDYL HYDROCHLORIDE (Pharmaceutical Associates), TRIHEXYPHENIDYL HYDROCHLORIDE (Qualitest Pharmaceuticals), TRIHEXYPHENIDYL HYDROCHLORIDE (REMEDYREPACK), TRIHEXYPHENIDYL HYDROCHLORIDE (REMEDYREPACK), TRIHEXYPHENIDYL HYDROCHLORIDE (REMEDYREPACK), TRIHEXYPHENIDYL HYDROCHLORIDE (REMEDYREPACK), TRIHEXYPHENIDYL HYDROCHLORIDE (REMEDYREPACK), TRIHEXYPHENIDYL HYDROCHLORIDE (REMEDYREPACK), TRIHEXYPHENIDYL HYDROCHLORIDE (REMEDYREPACK), TRIHEXYPHENIDYL HYDROCHLORIDE (REMEDYREPACK), TRIHEXYPHENIDYL HYDROCHLORIDE (Rising Pharmaceuticals), TRIHEXYPHENIDYL HYDROCHLORIDE (State of Florida DOH Central Pharmacy), TRIHEXYPHENIDYL HYDROCHLORIDE (State of Florida DOH Central Pharmacy), TRIHEXYPHENIDYL HYDROCHLORIDE (VersaPharm)
Formula
C20H31NO. HCl
Exact mass
337.2172
Mol weight
337.9272
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG01491  Muscarinic cholinergic receptor antagonist
  DG01745  Anticholinergic antiparkinson agent
 DG01745  Anticholinergic antiparkinson agent
 DG01967  Antiparkinson agent
  DG01745  Anticholinergic antiparkinson agent
Remark
Therapeutic category: 1169
ATC code: N04AA01
Chemical structure group: DG00851
Product (DG00851): D00787<JP/US>
Efficacy
Antiparkinsonian, Muscarinic acetylcholine receptor antagonist
  Disease
Parkinsonism [DS:H01600]
Target
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
Interaction
Drug interaction
Structure map
map07057  Antiparkinsonian agents
map07220  Cholinergic and anticholinergic drugs
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N04 ANTI-PARKINSON DRUGS
   N04A ANTICHOLINERGIC AGENTS
    N04AA Tertiary amines
     N04AA01 Trihexyphenidyl
      D00787  Trihexyphenidyl hydrochloride (JP17/USP) <JP/US>
USP drug classification [BR:br08302]
 Antiparkinson Agents
  Anticholinergics
   Trihexyphenidyl
    D00787  Trihexyphenidyl hydrochloride (JP17/USP)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   116  Antiparkinsonian agents
    1169  Others
     D00787  Trihexyphenidyl hydrochloride (JP17/USP)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    CHRM
     D00787  Trihexyphenidyl hydrochloride (JP17/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00787  Trihexyphenidyl hydrochloride
  D00787  Trihexyphenidyl hydrochloride tablets
BRITE hierarchy
Other DBs
CAS: 52-49-3
PubChem: 7847852
ChEBI: 9721
ChEMBL: CHEMBL1092
DrugBank: DB00376
LigandBox: D00787
NIKKAJI: J231.242E
KCF data Show

ATOM        23
            1   X   Cl   29.1405  -19.5417
            2   C8x C    27.3218  -23.9734
            3   C8x C    28.5397  -23.2839
            4   C8x C    28.5626  -21.9039
            5   C8x C    27.3331  -21.1525
            6   C8y C    26.1151  -21.8421
            7   C8x C    26.1268  -23.2830
            8   C1x C    26.1608  -19.0821
            9   C1y C    24.9429  -19.7716
            10  C1d C    24.9201  -21.1516
            11  C1x C    26.1492  -17.6412
            12  C1x C    24.9542  -16.9507
            13  C1x C    23.7362  -17.6402
            14  C1x C    23.7134  -19.0202
            15  C1b C    23.7021  -21.8411
            16  C1b C    22.5071  -21.1507
            17  N1y N    21.2892  -21.8402
            18  C1x C    20.0831  -21.1302
            19  C1x C    18.8651  -21.8198
            20  C1x C    18.8533  -23.2193
            21  C1x C    20.0594  -23.9292
            22  C1x C    21.2773  -23.2397
            23  O1a O    26.1325  -20.4516
BOND        24
            1     2   3 2
            2     3   4 1
            3     4   5 2
            4     5   6 1
            5     6   7 2
            6     2   7 1
            7     8   9 1
            8     9  10 1
            9     6  10 1
            10    8  11 1
            11   11  12 1
            12   12  13 1
            13   13  14 1
            14    9  14 1
            15   10  15 1
            16   15  16 1
            17   16  17 1
            18   17  18 1
            19   18  19 1
            20   19  20 1
            21   20  21 1
            22   21  22 1
            23   17  22 1
            24   10  23 1

» Japanese version   » Back

DBGET integrated database retrieval system