KEGG   DRUG: Acetophenazine maleateHelp
Entry
D00788                      Drug                                   

Name
Acetophenazine maleate (USAN);
Tindal (TN)
Formula
C23H29N3O2S. (C4H4O4)2
Exact mass
643.22
Mol weight
643.7046
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG01905  Phenothiazine antipsychotics
Remark
ATC code: N05AB07
Chemical structure group: DG00878
Efficacy
Antipsychotic
Comment
Phenothiazine derivative
Target
DRD2 [HSA:1813] [KO:K04145]
DRD1 [HSA:1812] [KO:K04144]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04728  Dopaminergic synapse
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N05 PSYCHOLEPTICS
   N05A ANTIPSYCHOTICS
    N05AB Phenothiazines with piperazine structure
     N05AB07 Acetophenazine
      D00788  Acetophenazine maleate (USAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Dopamine
    DRD1
     D00788  Acetophenazine maleate (USAN)
    DRD2
     D00788  Acetophenazine maleate (USAN)
BRITE hierarchy
Other DBs
CAS: 5714-00-1
PubChem: 7847853
ChEBI: 2402
ChEMBL: CHEMBL2360079
DrugBank: DB01063
LigandBox: D00788
NIKKAJI: J349.759C
KCF data Show

ATOM        45
            1   C8y C    15.9267  -18.6106
            2   N1y N    14.7166  -17.9089
            3   C8y C    15.9846  -20.0083
            4   C8x C    17.1366  -17.9210
            5   C8y C    13.4946  -18.6047
            6   C1b C    14.7106  -16.4993
            7   S2x S    14.7045  -20.7101
            8   C8x C    17.1185  -20.7222
            9   C8y C    18.3467  -18.6349
            10  C8y C    13.4885  -20.0083
            11  C8x C    12.2905  -17.9089
            12  C1b C    15.9267  -15.8096
            13  C8x C    18.3346  -20.0325
            14  C5a C    19.5566  -17.9271
            15  C8x C    12.2845  -20.7039
            16  C8x C    11.0624  -18.6047
            17  C1b C    15.9267  -14.4060
            18  C1a C    20.7605  -18.6228
            19  O5a O    19.5506  -16.5295
            20  C8x C    11.0624  -20.0083
            21  N1y N    17.1245  -13.7042
            22  C1x C    18.3467  -14.4060
            23  C1x C    17.1245  -12.3066
            24  C1x C    19.5566  -13.7042
            25  C1x C    18.3405  -11.6048
            26  N1y N    19.5566  -12.3006
            27  C1b C    20.7605  -11.6048
            28  C1b C    21.9765  -12.2945
            29  O1a O    23.1866  -11.6048
            30  C2b C    30.7057  -16.0108
            31  C2b C    29.0661  -16.0169
            32  C6a C    31.3833  -17.1905
            33  C6a C    28.3945  -17.2026
            34  O6a O    30.7117  -18.3704
            35  O6a O    32.7506  -17.2546
            36  O6a O    27.0334  -17.2026
            37  O6a O    29.0842  -18.3764
            38  C2b C    30.7057  -16.0108
            39  C2b C    29.0661  -16.0169
            40  C6a C    28.3945  -17.2026
            41  O6a O    27.0334  -17.2026
            42  O6a O    29.0842  -18.3764
            43  C6a C    31.3833  -17.1905
            44  O6a O    30.7117  -18.3704
            45  O6a O    32.7506  -17.2546
BOND        46
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     3   8 1
            8     4   9 2
            9     5  10 2
            10    5  11 1
            11    6  12 1
            12    8  13 2
            13    9  14 1
            14   10  15 1
            15   11  16 2
            16   12  17 1
            17   14  18 1
            18   14  19 2
            19   15  20 2
            20   17  21 1
            21   21  22 1
            22   21  23 1
            23   22  24 1
            24   23  25 1
            25   24  26 1
            26   26  27 1
            27   27  28 1
            28   28  29 1
            29    7  10 1
            30    9  13 1
            31   16  20 1
            32   25  26 1
            33   30  31 2
            34   30  32 1
            35   31  33 1
            36   32  34 1
            37   32  35 2
            38   33  36 1
            39   33  37 2
            40   38  39 2
            41   38  43 1
            42   39  40 1
            43   43  44 1
            44   43  45 2
            45   40  41 1
            46   40  42 2
BRACKET     1    25.2700  -19.9500   25.2700  -14.7000
            1    34.3700  -14.7000   34.3700  -19.9500
            1  2
 ORIGINAL  1   30  31  33  36  37  32  34  35
 REPEAT    1   38  39  40  41  42  43  44  45

» Japanese version   » Back

DBGET integrated database retrieval system