KEGG   DRUG: Mesoridazine besylateHelp
Entry
D00795                      Drug                                   

Name
Mesoridazine besylate (USP);
Serentil (TN)
Formula
C21H26N2OS2. C6H6O3S
Exact mass
544.1524
Mol weight
544.749
Structure
Mol fileKCF fileDB search
Class
Neuropsychiatric agent
 DG01905  Phenothiazine antipsychotics
Remark
ATC code: N05AC03
Chemical structure group: DG00883
Efficacy
Antipsychotic
Comment
Phenothiazine derivative
Target
DRD2 [HSA:1813] [KO:K04145]
HTR2A [HSA:3356] [KO:K04157]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04726  Serotonergic synapse
hsa04728  Dopaminergic synapse
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N05 PSYCHOLEPTICS
   N05A ANTIPSYCHOTICS
    N05AC Phenothiazines with piperidine structure
     N05AC03 Mesoridazine
      D00795  Mesoridazine besylate (USP)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Dopamine
    DRD2
     D00795  Mesoridazine besylate (USP)
   Serotonin
    HTR2A
     D00795  Mesoridazine besylate (USP)
BRITE hierarchy
Other DBs
CAS: 32672-69-8
PubChem: 7847860
ChEBI: 6781
ChEMBL: CHEMBL1201052
DrugBank: DB00933
LigandBox: D00795
NIKKAJI: J244.599I
KCF data Show

ATOM        36
            1   C8y C    19.7654  -18.6424
            2   N1y N    20.9836  -17.9429
            3   C8y C    19.7595  -20.0415
            4   C8x C    18.5528  -17.9369
            5   C8y C    22.1962  -18.6481
            6   C1b C    20.9778  -16.5438
            7   S2x S    20.9721  -20.7467
            8   C8x C    18.5528  -20.7410
            9   C8x C    17.3404  -18.6424
            10  C8y C    22.1845  -20.0472
            11  C8x C    23.4145  -17.9603
            12  C1b C    22.1903  -15.8443
            13  C8x C    17.3404  -20.0415
            14  C8x C    23.3853  -20.7526
            15  C8y C    24.5453  -18.6715
            16  C1y C    22.1903  -14.4511
            17  C8x C    24.6036  -20.0705
            18  C1x C    20.9778  -13.7457
            19  N1y N    23.3969  -13.7457
            20  C1x C    20.9778  -12.3525
            21  C1x C    23.3969  -12.3525
            22  C1x C    22.1903  -11.6587
            23  S4a S    25.7665  -17.9630
            24  C1a C    26.9870  -18.6641
            25  O1d O    25.7634  -16.5900
            26  C1a C    24.5875  -14.4284
            27  C8y C    32.2139  -17.8152
            28  C8x C    30.9955  -18.5205
            29  C8x C    33.4263  -18.5205
            30  S4a S    32.2022  -16.4162
            31  C8x C    30.9955  -19.9255
            32  C8x C    33.4263  -19.9255
            33  O1d O    32.1906  -15.0114
            34  O1d O    30.7974  -16.4162
            35  O1d O    33.6013  -16.4162
            36  C8x C    32.2139  -20.6191
BOND        39
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     3   8 1
            8     4   9 2
            9     5  10 2
            10    5  11 1
            11    6  12 1
            12    8  13 2
            13   10  14 1
            14   11  15 2
            15   12  16 1
            16   14  17 2
            17   16  18 1
            18   16  19 1
            19   18  20 1
            20   19  21 1
            21   20  22 1
            22    7  10 1
            23    9  13 1
            24   15  17 1
            25   21  22 1
            26   15  23 1
            27   23  24 1
            28   23  25 2
            29   19  26 1
            30   27  28 2
            31   27  29 1
            32   27  30 1
            33   28  31 1
            34   29  32 2
            35   30  33 1
            36   30  34 2
            37   30  35 2
            38   31  36 2
            39   32  36 1

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