KEGG   DRUG: Propiverine hydrochlorideHelp
Entry
D01007                      Drug                                   

Name
Propiverine hydrochloride (JP17);
Bup-4 (TN);
Mictonorm (TN)
Formula
C23H29NO3. HCl
Exact mass
403.1914
Mol weight
403.9422
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG01491  Muscarinic cholinergic receptor antagonist
Cyp substrate
 DG01633  CYP3A substrate
Remark
Therapeutic category: 2590
ATC code: G04BD06
Chemical structure group: DG00479
Product (DG00479): D01007<JP>
Efficacy
Antipollakisuria, Overactive bladder agent, Muscarinic acetylcholine receptor antagonist
Target
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
Metabolism
Enzyme: CYP3A4 [HSA:1576]
Interaction
Drug interaction
Structure map
map07220  Cholinergic and anticholinergic drugs
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 G GENITO URINARY SYSTEM AND SEX HORMONES
  G04 UROLOGICALS
   G04B UROLOGICALS
    G04BD Urinary antispasmodics
     G04BD06 Propiverine
      D01007  Propiverine hydrochloride (JP17) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  25  Urogenital and anal organ agents
   259  Miscellaneous
    2590  Miscellaneous
     D01007  Propiverine hydrochloride (JP17)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    CHRM
     D01007  Propiverine hydrochloride (JP17) <JP>
 Ion channels
  Voltage-gated ion channels
   Calcium channels
    CACNA1-L
     D01007  Propiverine hydrochloride (JP17) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01007  Propiverine hydrochloride
  D01007  Propiverine hydrochloride tablets
Drug classes of therapeutic agents [br08360.html]
 Endocrine and hormonal agents
  D01007
BRITE hierarchy
Other DBs
CAS: 54556-98-8
PubChem: 7848070
ChEBI: 8494
ChEMBL: CHEMBL2359059
LigandBox: D01007
NIKKAJI: J282.959B
KCF data Show

ATOM        28
            1   X   Cl   31.6971  -21.2255
            2   C1x C    19.9430  -20.7678
            3   N1y N    19.9430  -22.1663
            4   C1x C    21.1541  -22.8656
            5   C1x C    22.3654  -22.1663
            6   C1y C    22.3654  -20.7678
            7   C1x C    21.1541  -20.0686
            8   O7a O    23.6015  -20.0686
            9   C7a C    24.8128  -20.7678
            10  C1d C    26.0239  -20.0686
            11  C8y C    27.2350  -20.7678
            12  C8x C    28.4462  -20.0686
            13  C8x C    29.6573  -20.7678
            14  C8y C    26.0239  -18.6701
            15  C8x C    27.2371  -17.9696
            16  C8x C    27.2371  -16.5711
            17  C8x C    26.0259  -15.8718
            18  C8x C    24.8128  -16.5723
            19  C8x C    24.8128  -17.9708
            20  C8x C    27.2350  -22.1663
            21  C8x C    28.4462  -22.8656
            22  C8x C    29.6573  -22.1663
            23  O2a O    27.2350  -19.3693
            24  C1b C    28.4462  -18.6701
            25  C1b C    29.6780  -19.3815
            26  C1a C    30.8829  -18.6860
            27  O6a O    24.8128  -22.1661
            28  C1a C    18.7319  -22.8656
BOND        29
            1     2   3 1
            2     3   4 1
            3     4   5 1
            4     5   6 1
            5     6   7 1
            6     2   7 1
            7     6   8 1
            8     8   9 1
            9     9  10 1
            10   10  11 1
            11   11  12 1
            12   12  13 2
            13   10  14 1
            14   14  15 1
            15   15  16 2
            16   16  17 1
            17   17  18 2
            18   18  19 1
            19   14  19 2
            20   11  20 2
            21   20  21 1
            22   21  22 2
            23   22  13 1
            24   10  23 1
            25   23  24 1
            26   24  25 1
            27   25  26 1
            28    9  27 2
            29    3  28 1

» Japanese version   » Back

DBGET integrated database retrieval system