Entry |
|
Name |
Suplatast tosilate (JAN/INN); Suplatast tosylate; IPD (TN) |
Formula |
C16H26NO4S. C7H7O3S
|
Exact mass |
499.1698
|
Mol weight |
499.6406
|
Structure |
|
Class |
Dermatological agent
DG03243 Atopic dermatitis agent
|
Remark |
Therapeutic category: | 4490 |
|
Efficacy |
Antiallergic, Antiasthmatic |
Comment |
Th2 cytokine ( IL-4 [HSA: 3565], IL-5 [HSA: 3567] ) product inhibitor
See patyway of Asthema [PATH: hsa05310]
|
Brite |
Therapeutic category of drugs in Japan [BR:br08301]
4 Agents affecting cellular function
44 Allergic agents
449 Miscellaneous
4490 Miscellaneous
D01423 Suplatast tosilate (JAN/INN)
Drug groups [BR:br08330]
Dermatological agent
DG03243 Atopic dermatitis agent
D01423 Suplatast tosilate
Drug classes [BR:br08332]
Dermatological agent
DG03243 Atopic dermatitis agent
D01423 Suplatast tosilate
|
Other DBs |
|
KCF data |
ATOM 33
1 C8x C 23.6027 -16.5496
2 C8y C 23.6027 -17.9488
3 C8x C 24.8174 -18.6484
4 C8x C 26.0249 -17.9488
5 C8y C 26.0249 -16.5496
6 C8x C 24.8174 -15.8500
7 O2a O 22.3943 -18.6484
8 C1b C 21.1859 -17.9488
9 C1c C 19.9775 -18.6484
10 C1b C 18.7692 -17.9488
11 O2a O 17.5608 -18.6484
12 C1b C 16.3524 -17.9488
13 C1a C 15.1440 -18.6484
14 N1b N 27.2278 -15.8571
15 C5a C 28.4362 -16.5567
16 C1b C 29.6446 -15.8642
17 C1b C 30.8530 -16.5638
18 S0 S 32.0614 -15.8712 #+
19 O5a O 28.4293 -17.9559
20 O1a O 19.9706 -20.0475
21 C1a C 33.2710 -16.5747
22 C1a C 32.0660 -14.4720
23 C8y C 36.6613 -16.0237
24 C8x C 35.4390 -16.7255
25 C8x C 37.8776 -16.7255
26 S4a S 36.7136 -14.6201
27 C8x C 35.4390 -18.1289
28 C8x C 37.8776 -18.1289
29 O1d O 35.3101 -14.6201
30 O1d O 38.1232 -14.6201
31 O1d O 36.7079 -13.2165 #-
32 C8y C 36.6613 -18.8424
33 C1a C 36.6671 -20.2460
BOND 33
1 15 16 1
2 16 17 1
3 7 8 1
4 17 18 1
5 1 2 1
6 15 19 2
7 8 9 1
8 9 20 1
9 2 3 2
10 18 21 1
11 9 10 1
12 18 22 1
13 3 4 1
14 10 11 1
15 4 5 2
16 11 12 1
17 5 6 1
18 12 13 1
19 6 1 2
20 5 14 1
21 14 15 1
22 2 7 1
23 23 24 1
24 23 25 2
25 23 26 1
26 24 27 2
27 25 28 1
28 26 29 2
29 26 30 2
30 26 31 1
31 27 32 1
32 32 33 1
33 28 32 2
|