KEGG   DRUG: Ethyl piperidinoacetylaminobenzoateHelp
Entry
D01519                      Drug                                   

Name
Ethyl piperidinoacetylaminobenzoate (JAN);
Ethyl p-(2-piperidinoacetamido)benzoate;
Nichicaine (TN);
Sulcain (TN)
Formula
C16H22N2O3
Exact mass
290.163
Mol weight
290.3575
Structure
Mol fileKCF fileDB search
Remark
Therapeutic category: 1219
Product: D01519<JP>
Efficacy
Anesthetic (local)
Target
SCN1A [HSA:6323] [KO:K04833]
SCN2A [HSA:6326] [KO:K04834]
SCN3A [HSA:6328] [KO:K04836]
SCN4A [HSA:6329] [KO:K04837]
SCN5A [HSA:6331] [KO:K04838]
SCN8A [HSA:6334] [KO:K04840]
SCN9A [HSA:6335] [KO:K04841]
SCN10A [HSA:6336] [KO:K04842]
SCN11A [HSA:11280] [KO:K04843]
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  12  Agents affecting peripheral nervous system
   121  Local anesthetics
    1219  Others
     D01519  Ethyl piperidinoacetylaminobenzoate (JAN)
Risk category of Japanese OTC drugs [BR:br08312]
 Designated second-class OTC drugs
  Inorganic and organic chemicals
   Ethyl piperidinoacetylaminobenzoate
    D01519  Ethyl piperidinoacetylaminobenzoate (JAN)
 Second-class OTC drugs
  Inorganic and organic chemicals
   Ethyl piperidinoacetylaminobenzoate
    D01519  Ethyl piperidinoacetylaminobenzoate (JAN)
Target-based classification of drugs [BR:br08310]
 Ion channels
  Voltage-gated ion channels
   Sodium channels
    SCN1A
     D01519  Ethyl piperidinoacetylaminobenzoate (JAN) <JP>
    SCN2A
     D01519  Ethyl piperidinoacetylaminobenzoate (JAN) <JP>
    SCN3A
     D01519  Ethyl piperidinoacetylaminobenzoate (JAN) <JP>
    SCN4A
     D01519  Ethyl piperidinoacetylaminobenzoate (JAN) <JP>
    SCN5A
     D01519  Ethyl piperidinoacetylaminobenzoate (JAN) <JP>
    SCN8A
     D01519  Ethyl piperidinoacetylaminobenzoate (JAN) <JP>
    SCN9A
     D01519  Ethyl piperidinoacetylaminobenzoate (JAN) <JP>
    SCN10A
     D01519  Ethyl piperidinoacetylaminobenzoate (JAN) <JP>
    SCN11A
     D01519  Ethyl piperidinoacetylaminobenzoate (JAN) <JP>
BRITE hierarchy
Other DBs
CAS: 41653-21-8
PubChem: 7848582
ChEBI: 31576
ChEMBL: CHEMBL2106245
LigandBox: D01519
NIKKAJI: J87.242C
KCF data Show

ATOM        21
            1   C1x C    14.4832  -17.0470
            2   C1x C    14.4832  -15.6442
            3   C1x C    15.7009  -14.9428
            4   N1y N    16.9116  -15.6442
            5   C1x C    16.9116  -17.0470
            6   C1x C    15.7009  -17.7484
            7   C1b C    18.1177  -14.9498
            8   C5a C    19.3292  -15.6512
            9   N1b N    20.5407  -14.9569
            10  C8y C    21.7522  -15.6583
            11  C8x C    22.9654  -14.9598
            12  C8x C    24.1769  -15.6612
            13  C8y C    24.1752  -17.0611
            14  C8x C    22.9620  -17.7596
            15  C8x C    21.7505  -17.0582
            16  C7a C    25.3867  -17.7625
            17  O7a O    26.5982  -17.0683
            18  C1b C    27.8097  -17.7697
            19  C1a C    29.0212  -17.0752
            20  O5a O    19.3261  -17.0540
            21  O6a O    25.3836  -19.1653
BOND        22
            1     4   5 1
            2     5   6 1
            3     6   1 1
            4     4   7 1
            5    10  11 2
            6    11  12 1
            7    12  13 2
            8    13  14 1
            9    14  15 2
            10   15  10 1
            11    1   2 1
            12   13  16 1
            13    7   8 1
            14   16  17 1
            15    2   3 1
            16   17  18 1
            17    8   9 1
            18   18  19 1
            19    3   4 1
            20    8  20 2
            21    9  10 1
            22   16  21 2

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