| Entry |
|
|---|
| Name |
Acetylkitasamycin (JP18);
Neo-leucomycin H (TN) |
|---|
| Formula |
C41H64NO16R
|
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| Structure |
|
|---|
| Simcomp |
|
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| Class |
Antibacterial
DG01551 Macrolide antibiotic
DG01876 16-Membered ring macrolide antibiotic
|
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| Remark |
|
|---|
| Efficacy |
Antibacterial, Protein biosynthesis inhibitor |
|---|
| Comment |
R: See Acetylkitasamycin [CPD: C13074]
|
|---|
| Target |
50S ribosomal subunit |
|---|
| Pathway |
|
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| Interaction |
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| Structure map |
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| Brite |
Drug groups [BR:br08330]
Antibacterial
DG01551 Macrolide antibiotic
DG01876 16-Membered ring macrolide antibiotic
DG01203 Kitasamycin
D01614 Acetylkitasamycin
Antimicrobials [BR:br08307]
Antibacterials
Protein biosynthesis inhibitor
Macrolide
D01614 Acetylkitasamycin (JP18)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01614 Acetylkitasamycin
Drug groups [BR:br08330]
Antibacterial
DG01551 Macrolide antibiotic
DG01876 16-Membered ring macrolide antibiotic
DG01203 Kitasamycin
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Protein biosynthesis inhibitor
Macrolide
DG01203 Kitasamycin
|
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| Other DBs |
|
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| KCF data |
ATOM 59
1 C1y C 22.2968 -22.1697
2 C1y C 23.4014 -22.8158
3 O2a O 21.1968 -22.8158
4 C1y C 22.2968 -20.9008
5 C1y C 24.5181 -22.1697
6 N1c N 23.4014 -24.0917
7 C1y C 20.0979 -23.4508
8 O2x O 23.4014 -20.2656
9 C1y C 24.5181 -20.9008
10 O7a O 25.6239 -22.8158
11 C1a C 24.5069 -24.7256
12 C1a C 22.3026 -24.7256
13 C1x C 20.0979 -24.7199
14 O2x O 18.9810 -22.8158
15 O2a O 26.7458 -18.0246
16 C1z C 18.9810 -25.3660
17 C1y C 17.8764 -23.4508
18 C1y C 23.4097 -14.3748
19 C1y C 17.8764 -24.7199
20 C1a C 18.1198 -26.5845
21 O1a O 19.8773 -26.7432
22 C1a C 16.7821 -22.8158
23 C1y C 23.3809 -13.0654
24 C1y C 22.2585 -15.0382
25 O2a O 16.7821 -25.3660
26 C1x C 22.1948 -12.4249
27 C1b C 24.4275 -12.4191
28 C1y C 22.2873 -16.4155
29 O2a O 21.1005 -14.4086
30 C1y C 22.1948 -11.1390
31 C4a C 25.5387 -13.0486
32 C1x C 21.0780 -17.0050
33 C1y C 21.0723 -10.5040
34 C1a C 23.2937 -10.4984
35 O4a O 26.6375 -12.4023
36 C7x C 19.9215 -16.3644
37 C2x C 19.9734 -11.1390
38 O7a O 21.0723 -9.2359
39 O7x O 18.7664 -16.9994
40 O6a O 19.9215 -15.0887
41 C2x C 19.9734 -12.4249
42 C1y C 17.6271 -16.3069
43 C2x C 18.8452 -13.0654
44 C1x C 17.6102 -14.9580
45 C1a C 16.5045 -16.9193
46 C2x C 18.8283 -14.3578
47 C1a C 21.0669 -13.1388
48 O7a O 23.3770 -17.0838
49 C7a C 26.7934 -22.1487
50 C1a C 27.9560 -22.8279
51 O6a O 26.8005 -20.8022
52 C7a C 23.3782 -18.4303
53 C1a C 22.2126 -19.1043
54 O6a O 24.5449 -19.1025
55 C7a C 22.1705 -8.6017
56 O6a O 22.1705 -7.3336
57 C1a C 23.2687 -9.2359
58 C1a C 21.1984 -20.2651
59 R R 15.5687 -24.6811
BOND 61
1 24 29 1 #Down
2 26 30 1
3 27 31 1
4 28 32 1
5 30 33 1
6 30 34 1 #Down
7 31 35 2
8 32 36 1
9 33 37 1
10 33 38 1 #Down
11 36 39 1
12 36 40 2
13 37 41 2
14 39 42 1
15 41 43 1
16 42 44 1
17 42 45 1 #Down
18 43 46 2
19 8 9 1
20 17 19 1
21 44 46 1
22 29 47 1
23 1 2 1
24 1 3 1 #Down
25 1 4 1
26 2 5 1
27 2 6 1 #Up
28 7 3 1 #Up
29 4 8 1
30 5 9 1
31 5 10 1 #Down
32 6 11 1
33 28 48 1 #Down
34 6 12 1
35 7 13 1
36 7 14 1
37 9 15 1 #Up
38 13 16 1
39 10 49 1
40 14 17 1
41 49 50 1
42 18 15 1 #Down
43 49 51 2
44 16 19 1
45 48 52 1
46 16 20 1 #Down
47 52 53 1
48 16 21 1 #Up
49 52 54 2
50 17 22 1 #Down
51 38 55 1
52 18 23 1
53 55 56 2
54 18 24 1
55 55 57 1
56 19 25 1 #Up
57 4 58 1 #Up
58 23 26 1
59 23 27 1 #Down
60 24 28 1
61 25 59 1
|
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