KEGG   DRUG: Voglibose
Entry
D01665                      Drug                                   
Name
Voglibose (JP18/USAN/INN);
Basen (TN)
Formula
C10H21NO7
Exact mass
267.1318
Mol weight
267.2762
Structure
Class
Antidiabetic agent
 DG02044  Hypoglycemic agent
  DG01663  alpha-Glucosidase inhibitor
Remark
Therapeutic category: 3969
ATC code: A10BF03
Product: D01665<JP>
Product (mixture): D10160<JP>
Efficacy
Antidiabetic, alpha-Glucosidase inhibitor
Comment
alpha-glucosidase inhibitors
Target
GAA [HSA:2548] [KO:K12316]
GANC [HSA:2595] [KO:K12317]
MGAM [HSA:8972] [KO:K12047]
  Pathway
hsa00052  Galactose metabolism
hsa00500  Starch and sucrose metabolism
hsa04973  Carbohydrate digestion and absorption
Interaction
Structure map
map07051  Antidiabetics
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A10 DRUGS USED IN DIABETES
   A10B BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
    A10BF Alpha glucosidase inhibitors
     A10BF03 Voglibose
      D01665  Voglibose (JP18/USAN/INN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 3  Agents affecting metabolism
  39  Other agents affecting metabolism
   396  Antidiabetic agents
    3969  Others
     D01665  Voglibose (JP18/USAN/INN)
Drug groups [BR:br08330]
 Antidiabetic agent
  DG02044  Hypoglycemic agent
   DG01663  alpha-Glucosidase inhibitor
    D01665  Voglibose
Drug classes [BR:br08332]
 Antidiabetic agent
  DG01663  alpha-Glucosidase inhibitor
   D01665  Voglibose
  DG02044  Hypoglycemic agent
   D01665  Voglibose
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases (EC3)
   Glycosidases
    GAA
     D01665  Voglibose (JP18/USAN/INN) <JP>
    GANC
     D01665  Voglibose (JP18/USAN/INN) <JP>
    MGAM
     D01665  Voglibose (JP18/USAN/INN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01665  Voglibose
  D01665  Voglibose tablets
  D01665  Voglibose orally disintegrating tablets
Other DBs
CAS: 83480-29-9
PubChem: 7848728
ChEBI: 32300
PDB-CCD: VOG[PDBj]
LigandBox: D01665
NIKKAJI: J248.129D J556.821H
KCF data

ATOM        18
            1   C1y C     8.6100   -9.6600
            2   C1y C     8.6100  -11.0600
            3   C1y C     9.8224  -11.7600
            4   C1y C    11.0349  -11.0600
            5   C1x C    11.0349   -9.6600
            6   C1z C     9.8224   -8.9600
            7   C1b C     9.8224   -7.5602
            8   O1a O     7.3976  -11.7600
            9   O1a O     7.3976   -8.9600
            10  O1a O     9.8224  -13.1598
            11  N1b N    12.2660  -11.7710
            12  O1a O    11.0349   -8.2600
            13  C1c C    13.4712  -11.0753
            14  C1b C    14.6535  -11.7581
            15  C1b C    13.4716   -9.6604
            16  O1a O    14.6605   -8.9741
            17  O1a O    15.8475  -11.0688
            18  O1a O    11.0180   -6.8698
BOND        18
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     6   7 1 #Up
            8     2   8 1 #Up
            9     1   9 1 #Down
            10    3  10 1 #Down
            11    4  11 1 #Down
            12    6  12 1 #Down
            13   11  13 1
            14   13  14 1
            15   13  15 1
            16   15  16 1
            17   14  17 1
            18    7  18 1

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