KEGG   DRUG: Oxprenolol hydrochlorideHelp
Entry
D01806                      Drug                                   

Name
Oxprenolol hydrochloride (JP17/USP);
Okuspurecol (TN)
Formula
C15H23NO3. HCl
Exact mass
301.1445
Mol weight
301.809
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Cardiovascular agent
 DG01653  Antiarrhythmics
  DG01806  Class II antiarrhythmic agent
 DG01466  Adrenergic receptor antagonist
  DG01464  beta-Adrenergic receptor antagonist
   DG01461  beta1-Adrenergic receptor antagonist
   DG01462  beta2-Adrenergic receptor antagonist
   DG01463  beta3-Adrenergic receptor antagonist
Remark
ATC code: C07AA02
Chemical structure group: DG00304
Efficacy
Antiarrhythmic, Vasodilator, beta-Adrenergic receptor antagonist
Comment
Propranolol derivative
Target
ADRB [HSA:153 154 155] [KO:K04141 K04142 K04143]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C07 BETA BLOCKING AGENTS
   C07A BETA BLOCKING AGENTS
    C07AA Beta blocking agents, non-selective
     C07AA02 Oxprenolol
      D01806  Oxprenolol hydrochloride (JP17/USP)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    ADRB
     D01806  Oxprenolol hydrochloride (JP17/USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01806  Oxprenolol hydrochloride
BRITE hierarchy
Other DBs
CAS: 6452-73-9
PubChem: 7848868
ChEBI: 31949
ChEMBL: CHEMBL1200745
LigandBox: D01806
NIKKAJI: J369.034B
KCF data Show

ATOM        20
            1   X   Cl   18.2097  -28.2160
            2   O2a O    11.6200  -24.2200
            3   C1b C    12.8100  -23.5200
            4   C1c C    14.0700  -24.2200
            5   C1b C    15.2600  -23.5200
            6   N1b N    16.4500  -24.2200
            7   C1c C    17.7100  -23.5200
            8   C1a C    18.9000  -24.2200
            9   O1a O    14.0700  -25.6200
            10  C1a C    17.7100  -22.1200
            11  C8y C    11.6200  -25.6200
            12  C8y C    10.4076  -26.3200
            13  C8x C    10.4076  -27.7200
            14  C8x C    11.6200  -28.4200
            15  C8x C    12.8324  -27.7200
            16  C8x C    12.8324  -26.3200
            17  O2a O     9.2121  -25.6296
            18  C1b C     8.0247  -26.3151
            19  C2b C     6.8335  -25.6271
            20  C2a C     5.6440  -26.3138
BOND        19
            1     4   5 1
            2     5   6 1
            3     6   7 1
            4     7   8 1
            5     4   9 1
            6     7  10 1
            7     2   3 1
            8     3   4 1
            9     2  11 1
            10   11  12 2
            11   12  13 1
            12   13  14 2
            13   14  15 1
            14   15  16 2
            15   11  16 1
            16   12  17 1
            17   17  18 1
            18   18  19 1
            19   19  20 2

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