KEGG   DRUG: Tiquizium bromideHelp
Entry
D01875                      Drug                                   

Name
Tiquizium bromide (JAN/INN);
Thiaton (TN)
Formula
C19H24NS2. Br
Exact mass
409.0534
Mol weight
410.4346
Structure
Mol fileKCF fileDB search
Class
Neuropsychiatric agent
 DG01491  Muscarinic cholinergic receptor antagonist
Gastrointestinal agent
 DG01975  Agents for peptic ulcer
Remark
Therapeutic category: 1231
Product: D01875<JP>
Efficacy
Antispasmodic, Muscarinic acetylcholine receptor antagonist
Target
CHRM3 [HSA:1131] [KO:K04131]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
hsa04971  Gastric acid secretion
Interaction
Drug interaction
Structure map
map07038  Antiulcer drugs
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  12  Agents affecting peripheral nervous system
   123  Autonomic nervous system agents
    1231  Quaternary ammoniums
     D01875  Tiquizium bromide (JAN/INN)
Classification of Japanese OTC drugs [BR:br08313]
 Agents for digestive organs
  15 Stomach pain and cramp relievers
   D01875  Tiquizium bromide (JAN/INN)
Risk category of Japanese OTC drugs [BR:br08312]
 Second-class OTC drugs
  Inorganic and organic chemicals
   Tiquizium
    D01875  Tiquizium bromide (JAN/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    CHRM3
     D01875  Tiquizium bromide (JAN/INN) <JP>
Rx-to-OTC switch list in Japan [br08314.html]
 D01875
BRITE hierarchy
Other DBs
CAS: 71731-58-3
PubChem: 7848937
ChEBI: 32232
ChEMBL: CHEMBL2104533 CHEMBL2360047
LigandBox: D01875
NIKKAJI: J349.600G
KCF data Show

ATOM        23
            1   C1x C    20.5800  -23.9400
            2   C1x C    21.7700  -23.3100
            3   C2y C    21.7700  -21.9100
            4   C1x C    20.5800  -21.2100
            5   C2c C    23.0300  -21.2800
            6   C8y C    24.1500  -21.9800
            7   C8y C    23.0300  -19.8800
            8   C8x C    21.9423  -19.0650
            9   C8x C    22.4162  -17.7532
            10  C8x C    23.7480  -17.7375
            11  S2x S    24.1833  -19.0864
            12  C8x C    24.6400  -23.2400
            13  C8x C    26.0400  -23.1700
            14  C8x C    26.3900  -21.8400
            15  S2x S    25.2700  -21.0700
            16  C1y C    19.3900  -23.2400
            17  N2y N    19.3900  -21.9100 #+
            18  C1x C    18.2000  -21.2100
            19  C1x C    17.0100  -21.8400
            20  C1x C    17.0100  -23.2400
            21  C1x C    18.2000  -23.9400
            22  C1a C    19.3900  -19.8800
            23  X   Br   18.1300  -18.9700 #-
BOND        25
            1     8   9 1
            2     9  10 2
            3    10  11 1
            4    11   7 1
            5    16   1 1
            6     1   2 1
            7     6  12 2
            8    12  13 1
            9    13  14 2
            10   14  15 1
            11   15   6 1
            12    2   3 1
            13    3   5 2
            14    3   4 1
            15    5   6 1
            16   16  17 1
            17   17  18 1
            18   18  19 1
            19   19  20 1
            20   20  21 1
            21   21  16 1
            22    4  17 1
            23    5   7 1
            24   17  22 1 #Up
            25    7   8 2

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