| Entry |
|
|---|
| Name |
Pentazocine hydrochloride (JAN/USP);
Sosegon (TN);
Talacen (TN) |
|---|
| Formula |
C19H27NO. HCl
|
|---|
| Exact mass |
321.1859
|
|---|
| Mol weight |
321.8847
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01564 Opioid receptor agonist
Analgesic
DG01984 Opioid analgesics
|
|---|
| Remark |
| Therapeutic category: | 1149 |
| Product (DG00819): | D00498<JP> D02227<JP> |
| Product (mixture): | D12492<US> |
|
|---|
| Efficacy |
Analgesic, Opioid receptor agonist/antagonist |
|---|
| Comment |
Benzomorphan derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07224 | Opioid receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N02 ANALGESICS
N02A OPIOIDS
N02AD Benzomorphan derivatives
N02AD01 Pentazocine
D02227 Pentazocine hydrochloride (JAN/USP) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
114 Antipyretics and analgesics, anti-inflammatory agents
1149 Others
D02227 Pentazocine hydrochloride (JAN/USP)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG00819 Pentazocine
D02227 Pentazocine hydrochloride
Analgesic
DG01984 Opioid analgesics
DG00819 Pentazocine
D02227 Pentazocine hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Opioid
OPRM1
D02227 Pentazocine hydrochloride (JAN/USP) <JP>
OPRK1
D02227 Pentazocine hydrochloride (JAN/USP) <JP>
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG00819 Pentazocine
Analgesic
DG01984 Opioid analgesics
DG00819 Pentazocine
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 22
1 X Cl 38.7586 -17.6371
2 C1z C 32.2000 -20.1600
3 C8y C 32.2000 -18.8300
4 C1y C 33.4600 -20.8600
5 C1a C 31.0800 -20.7900
6 C1x C 33.4600 -19.5300
7 C8x C 31.0800 -18.2000
8 C8y C 33.4600 -18.2000
9 C1y C 34.5800 -20.1600
10 C1x C 35.7000 -19.5300
11 C8y C 31.0800 -16.8700
12 C1x C 34.5800 -18.9000
13 C8x C 33.4600 -16.8700
14 N1y N 35.7000 -20.8600
15 C8x C 32.2700 -16.1700
16 O1a O 29.9600 -16.1700
17 C1b C 37.1000 -20.8600
18 C2b C 37.8700 -22.1200
19 C1a C 33.4600 -22.3300
20 C2c C 39.2700 -22.1200
21 C1a C 39.9700 -23.3800
22 C1a C 39.9700 -20.8600
BOND 23
1 2 3 1
2 2 4 1
3 2 5 1
4 2 6 1 #Up
5 3 7 2
6 3 8 1
7 4 9 1
8 6 10 1
9 7 11 1
10 8 12 1
11 8 13 2
12 9 14 1 #Up
13 11 15 2
14 11 16 1
15 9 12 1
16 10 14 1
17 13 15 1
18 14 17 1
19 17 18 1
20 4 19 1 #Down
21 18 20 2
22 20 21 1
23 20 22 1
|
|---|
