| Entry |
|
|---|
| Name |
Dipivefrin (USAN);
Dipivefrine (INN)
|
|---|
| Formula |
C19H29NO5
|
|---|
| Exact mass |
351.2046
|
|---|
| Mol weight |
351.4373
|
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| Structure |
   |
|---|
| Simcomp |
 |
|---|
| Class |
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01450 alpha-Adrenergic receptor agonist
DG01448 alpha1-Adrenergic receptor agonist
DG01449 alpha2-Adrenergic receptor agonist
DG01455 beta-Adrenergic receptor agonist
DG01451 beta1-Adrenergic receptor agonist
DG01452 beta2-Adrenergic receptor agonist
DG01453 beta3-Adrenergic receptor agonist
DG01951 Catecholamine adrenergic receptor agonist
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist
DG01461 beta1-Adrenergic receptor antagonist
|
|---|
| Remark |
| Product (DG01129): | D01017<JP> |
|
|---|
| Efficacy |
Antiglaucoma, Adrenergic receptor agonist |
|---|
| Comment |
Active form of prodrug: Adrenaline (Epinephrine) [DR: D00095]
Catecholamine derivative
|
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| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04270 | Vascular smooth muscle contraction |
|
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| Interaction |
|
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| Structure map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
S01EA Sympathomimetics in glaucoma therapy
S01EA02 Dipivefrine
D02349 Dipivefrin (USAN)
USP drug classification [BR:br08302]
Ophthalmic Agents
Ophthalmic Antiglaucoma Agents
Dipivefrin
D02349 Dipivefrin (USAN)
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA1
D02349 Dipivefrin (USAN)
ADRA2
D02349 Dipivefrin (USAN)
ADRB
D02349 Dipivefrin (USAN)
Prodrugs [br08324.html]
DG01129
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| Other DBs |
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| KCF data |
ATOM 25
1 C8y C 10.7100 -23.0300
2 C8y C 10.7100 -24.4300
3 C8x C 11.9000 -22.3300
4 O7a O 9.5200 -22.3300
5 C8x C 11.9700 -25.0600
6 O7a O 9.5900 -25.0600
7 C8y C 13.1600 -22.9600
8 C7a C 9.5200 -21.0000
9 C8x C 13.1600 -24.3600
10 C1c C 14.3500 -22.2600
11 C1d C 8.2600 -20.3000
12 O6a O 10.7100 -20.2300
13 C1b C 15.5400 -22.8900
14 O1a O 14.3500 -20.8600
15 N1b N 16.7394 -22.1679
16 C1a C 17.9665 -22.8466
17 C7a C 9.5900 -26.4600
18 C1d C 8.3776 -27.1600
19 O6a O 10.8024 -27.1600
20 C1a C 7.1821 -26.4696
21 C1a C 8.3775 -28.5598
22 C1a C 7.1820 -27.8503
23 C1a C 7.0593 -21.0199
24 C1a C 8.2369 -18.9002
25 C1a C 7.0362 -19.6201
BOND 25
1 1 2 1
2 1 3 2
3 1 4 1
4 2 5 2
5 2 6 1
6 3 7 1
7 4 8 1
8 5 9 1
9 7 10 1
10 8 11 1
11 8 12 2
12 10 13 1
13 10 14 1
14 7 9 2
15 13 15 1
16 15 16 1
17 6 17 1
18 17 18 1
19 17 19 2
20 18 20 1
21 18 21 1
22 18 22 1
23 11 23 1
24 11 24 1
25 11 25 1
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