KEGG   DRUG: SuccinylsulfathiazoleHelp
Entry
D02447                      Drug                                   

Name
Succinylsulfathiazole;
Succinylsulfathiazole monohydrate;
Sulfasuxidine (TN)
Formula
C13H13N3O5S2. H2O
Exact mass
373.0402
Mol weight
373.4047
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Antibacterial
 DG01787  Sulfonamide antibacterial
  DG01784  Short-acting sulfonamide
Remark
ATC code: A07AB04
Chemical structure group: DG00088
Efficacy
Antibacterial, Folic acid biosynthesis inhibitor
Comment
Sulfonamide
Active form of prodrug: Sulfathiazole [DR:D01047]
Target
dihydropteroate synthase [KO:K00796]
  Pathway
ko00790  Folate biosynthesis
Interaction
Drug interaction
Structure map
map07016  Sulfonamide derivatives - sulfa drugs
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
   A07A INTESTINAL ANTIINFECTIVES
    A07AB Sulfonamides
     A07AB04 Succinylsulfathiazole
      D02447  Succinylsulfathiazole
Prodrugs [br08324.html]
 DG00088
BRITE hierarchy
Other DBs
CAS: 6101-17-3
PubChem: 7849505
LigandBox: D02447
KCF data Show

ATOM        24
            1   C1b C    13.0356  -17.4752
            2   C5a C    14.2420  -16.7670
            3   N1b N    15.4484  -17.5274
            4   O5a O    14.2304  -15.3752
            5   C8y C    16.7130  -16.8482
            6   C8x C    16.7539  -15.4562
            7   C8x C    17.8674  -17.5563
            8   C8x C    17.8965  -14.7724
            9   C8x C    19.0727  -16.8715
            10  C8y C    19.0200  -15.4853
            11  S4a S    20.3024  -14.8073
            12  N1b N    21.4973  -15.5084
            13  O3c O    19.3056  -13.8036
            14  O3c O    21.4973  -14.0933
            15  C1b C    11.8242  -16.7813
            16  C6a C    10.6201  -17.4879
            17  O6a O     9.4084  -16.8015
            18  O6a O    10.6270  -18.8886
            19  C8y C    22.7298  -14.8087
            20  S2x S    23.8736  -15.6317
            21  C8x C    25.0136  -14.7974
            22  C8x C    24.5723  -13.4554
            23  N5x N    23.1596  -13.4603
            24  O0  O    27.9386  -16.0688
BOND        24
            1     3   5 1
            2     5   6 2
            3     5   7 1
            4     6   8 1
            5     7   9 2
            6     8  10 2
            7    10  11 1
            8    11  12 1
            9    11  13 2
            10   11  14 2
            11    9  10 1
            12    1  15 1
            13    1   2 1
            14   15  16 1
            15    2   3 1
            16    2   4 2
            17   16  17 1
            18   16  18 2
            19   12  19 1
            20   19  20 1
            21   20  21 1
            22   21  22 2
            23   22  23 1
            24   19  23 2

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