KEGG   DRUG: RemoxiprideHelp
Entry
D02682                      Drug                                   

Name
Remoxipride (USAN)
Formula
C16H23BrN2O3
Exact mass
370.0892
Mol weight
371.2694
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG01941  Benzamide antipsychotic
 DG01478  Dopamine antagonist
  DG01474  Dopamine D2-receptor antagonist
Remark
ATC code: N05AL04
Chemical structure group: DG00902
Efficacy
Antipsychotic, Dopamine D2 receptor antagonist
Comment
Benzamide derivative
Target
DRD2 [HSA:1813] [KO:K04145]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04540  Gap junction
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N05 PSYCHOLEPTICS
   N05A ANTIPSYCHOTICS
    N05AL Benzamides
     N05AL04 Remoxipride
      D02682  Remoxipride (USAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Dopamine
    DRD2
     D02682  Remoxipride (USAN)
BRITE hierarchy
Other DBs
CAS: 80125-14-0
PubChem: 17396851
ChEMBL: CHEMBL22242
DrugBank: DB00409
LigandBox: D02682
NIKKAJI: J138.394I
KCF data Show

ATOM        22
            1   C8y C    13.7120  -16.4727
            2   C8x C    13.7120  -15.0665
            3   C8x C    14.9776  -14.3634
            4   C8y C    14.9776  -17.1758
            5   C8y C    16.1729  -16.4727
            6   C8y C    16.1729  -15.0665
            7   O2a O    17.3681  -14.3634
            8   C5a C    17.3681  -17.1758
            9   N1b N    18.6337  -16.4727
            10  C1b C    19.8290  -17.1758
            11  O5a O    17.3681  -18.5820
            12  C1a C    17.3681  -12.9572
            13  C1y C    21.0946  -16.5430
            14  N1y N    22.2195  -17.3164
            15  C1x C    23.3445  -16.4727
            16  C1x C    22.8523  -15.2071
            17  C1x C    21.5164  -15.2071
            18  C1b C    22.2195  -18.6523
            19  C1a C    23.4851  -19.3554
            20  O2a O    14.9949  -18.5819
            21  C1a C    13.7731  -19.3076
            22  X   Br   12.5212  -17.1732
BOND        23
            1     9   8 1
            2     8   5 1
            3     1   2 2
            4     2   3 1
            5    10   9 1
            6     3   6 2
            7     5   4 2
            8     4   1 1
            9     8  11 2
            10    5   6 1
            11    6   7 1
            12    7  12 1
            13   13  10 1 #Down
            14   13  14 1
            15   14  15 1
            16   15  16 1
            17   16  17 1
            18   13  17 1
            19   14  18 1
            20   18  19 1
            21    4  20 1
            22   20  21 1
            23    1  22 1

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