KEGG   DRUG: TeceleukinHelp
Entry
D02749                      Drug                                   

Name
Teceleukin (USAN);
Teceleukin (genetical recombination) (JP17);
Imunace (TN)
Formula
C698H1127N179O204S8
Exact mass
15537.1082
Mol weight
15547.0139
Sequence
MAPTSSSTKK TQLQLEHLLL DLQMILNGIN NYKNPKLTRM LTFKFYMPKK ATELKHLQCL
EEELKPLEEV LNLAQSKNFH LRPRDLISNI NVIVLELKGS ETTFMCEYAD ETATIVEFLN
RWITFCQSII STLT (Disulfid bridge: 59-106)
  Type
Peptide
Remark
Therapeutic category: 6399
Product: D02749<JP>
Efficacy
Antineoplastic, Immunostimulant, Biological response modifier
Comment
recombinant interleukin 2 [HSA:3558] [KO:K05429]
Target
IL2RA (CD25) [HSA:3559] [KO:K05068]
IL2RB (CD122) [HSA:3560] [KO:K05069]
IL2RG (CD132) [HSA:3561] [KO:K05070]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04630  JAK-STAT signaling pathway
Interaction
Drug interaction
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  63  Biological preparations
   639  Miscellaneous
    6399  Others
     D02749  Teceleukin (USAN); Teceleukin (genetical recombination) (JP17)
Target-based classification of drugs [BR:br08310]
 Cytokines and receptors
  Cytokine receptors
   Interleukin receptors
    IL2RA (CD25)
     D02749  Teceleukin (USAN) <JP>
    IL2RB (CD122)
     D02749  Teceleukin (USAN) <JP>
    IL2RG (CD132)
     D02749  Teceleukin (USAN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D02749  Teceleukin (genetical recombination)
  D02749  Teceleukin for injection (genetical recombination)
BRITE hierarchy
Other DBs
CAS: 136279-32-8
PubChem: 47205821

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