KEGG   DRUG: AbciximabHelp
Entry
D02778                      Drug                                   

Name
Abciximab (USAN/INN);
Abciximab (genetical recombination) (JAN);
Reopro (TN)
Product
Formula
C2109H3243N553O674S15
Exact mass
47580.23
Mol weight
47609.5914
Class
Cardiovascular agent
 DG01712  Antiplatelet agent
 DG01950  Antithrombotic agent
  DG01712  Antiplatelet agent
 DG01811  Fibrinogen receptor antagonist
Remark
ATC code: B01AC13
Product: D02778<US>
Efficacy
Platelet aggregation inhibitor, Glycoprotein IIb/IIIa receptor antagonist
Comment
Monoclonal antibody
Target
ITGA2B/ITGB3 [HSA:3674 3690] [KO:K06476 K06493]
  Pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
Interaction
Drug interaction
Structure map
map07049  Antithrombosis agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 B BLOOD AND BLOOD FORMING ORGANS
  B01 ANTITHROMBOTIC AGENTS
   B01A ANTITHROMBOTIC AGENTS
    B01AC Platelet aggregation inhibitors excl. heparin
     B01AC13 Abciximab
      D02778  Abciximab (USAN/INN) <US>
Target-based classification of drugs [BR:br08310]
 Cell surface molecules and ligands
  Cell adhesion molecules: other families
   Integrins
    ITGA2B/ITGB3
     D02778  Abciximab (USAN/INN) <US>
BRITE hierarchy
Other DBs
CAS: 143653-53-6
PubChem: 17396936
DrugBank: DB00054
NIKKAJI: J2.137.234J

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