KEGG   DRUG: Alprenoxime hydrochlorideHelp
Entry
D02834                      Drug                                   

Name
Alprenoxime hydrochloride (USAN)
Formula
C15H22N2O2. HCl
Exact mass
298.1448
Mol weight
298.8083
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Cardiovascular agent
 DG01466  Adrenergic receptor antagonist
  DG01464  beta-Adrenergic receptor antagonist
   DG01461  beta1-Adrenergic receptor antagonist
   DG01462  beta2-Adrenergic receptor antagonist
   DG01463  beta3-Adrenergic receptor antagonist
Efficacy
Antiglaucoma, beta-Adrenergic receptor antagonist
Target
ADRB [HSA:153 154 155] [KO:K04141 K04142 K04143]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04970  Salivary secretion
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    ADRB
     D02834  Alprenoxime hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 121009-30-1
PubChem: 17396991
ChEMBL: CHEMBL2448147
LigandBox: D02834
KCF data Show

ATOM        20
            1   C8x C    14.9100  -14.8400
            2   C8x C    13.6976  -15.5400
            3   C8x C    13.6976  -16.9400
            4   C8x C    14.9100  -17.6400
            5   C8y C    16.1224  -16.9400
            6   C8y C    16.1224  -15.5400
            7   C1b C    17.3349  -17.6400
            8   C2b C    18.5473  -16.9400
            9   C1b C    18.5473  -15.5400
            10  O2a O    17.3349  -14.8400
            11  C2a C    19.7597  -17.6400
            12  C1b C    20.9722  -15.5400
            13  C2c C    19.7597  -14.8400
            14  N1b N    22.1846  -14.8400
            15  O1b O    20.9721  -12.7400
            16  N2b N    19.7597  -13.4400
            17  C1a C    23.3971  -16.9399
            18  C1c C    23.3971  -15.5399
            19  C1a C    24.6095  -14.8399
            20  X   Cl   28.4900  -16.0300
BOND        19
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     9  10 1
            10    6  10 1
            11    8  11 2
            12   12  13 1
            13    9  13 1
            14   12  14 1
            15   15  16 1
            16   13  16 2
            17   17  18 1
            18   14  18 1
            19   18  19 1

» Japanese version   » Back

DBGET integrated database retrieval system