| Entry |
|
|---|
| Name |
Cicloprolol hydrochloride (USAN) |
|---|
| Formula |
C18H29NO4. HCl
|
|---|
| Exact mass |
359.1863
|
|---|
| Mol weight |
359.8881
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG01461 beta1-Adrenergic receptor antagonist
|
|---|
| Efficacy |
Antihypertensive, beta1-Adrenergic receptor antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG01461 beta1-Adrenergic receptor antagonist
D03490 Cicloprolol hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRB1
D03490 Cicloprolol hydrochloride (USAN)
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 24
1 O2a O 19.4600 -16.8700
2 C1b C 20.7200 -16.1700
3 C1c C 21.9100 -16.8700
4 C1b C 23.1000 -16.1700
5 O1a O 21.9100 -18.2700
6 N1b N 24.2900 -16.8700
7 C1c C 25.4800 -16.1700
8 C1a C 26.6700 -16.8700
9 C1a C 25.4800 -14.7700
10 C8y C 19.4600 -18.2700
11 C8x C 18.2000 -18.9700
12 C8x C 18.2000 -20.3700
13 C8y C 19.3900 -21.0700
14 C8x C 20.6500 -20.3700
15 C8x C 20.6500 -18.9700
16 O2a O 19.3900 -22.4700
17 C1b C 18.2000 -23.1700
18 C1b C 17.0100 -22.4700
19 O2a O 15.7500 -23.1700
20 C1b C 14.5600 -22.4000
21 C1y C 13.3700 -23.1000
22 C1x C 11.9700 -23.1000
23 C1x C 12.6700 -24.2900
24 X Cl 26.1800 -21.7000
BOND 24
1 1 2 1
2 2 3 1
3 3 4 1
4 3 5 1
5 4 6 1
6 6 7 1
7 7 8 1
8 7 9 1
9 1 10 1
10 10 11 2
11 11 12 1
12 12 13 2
13 13 14 1
14 14 15 2
15 10 15 1
16 13 16 1
17 16 17 1
18 17 18 1
19 18 19 1
20 19 20 1
21 20 21 1
22 22 21 1
23 23 22 1
24 21 23 1
|
|---|
