KEGG   DRUG: Dazmegrel
Entry
D03661                      Drug                                   

Name
Dazmegrel (USAN/INN)
Formula
C16H17N3O2
Exact mass
283.1321
Mol weight
283.3251
Structure
Class
Cardiovascular agent
 DG01712  Antiplatelet agent
  DG01516  Thromboxane A2 synthase inhibitor
 DG01950  Antithrombotic agent
  DG01712  Antiplatelet agent
   DG01516  Thromboxane A2 synthase inhibitor
 DG01516  Thromboxane A2 synthase inhibitor
Efficacy
Platelet aggregation inhibitor, Thromboxane A2 (TXA2) synthase inhibitor
Target
TBXAS1 (CYP5A1) [HSA:6916] [KO:K01832]
  Pathway
hsa00590  Arachidonic acid metabolism
hsa04611  Platelet activation
Interaction
Brite
Target-based classification of drugs [BR:br08310]
 Enzymes
  Isomerases (EC5)
   Thromboxane-A synthase
    TBXAS1 (CYP5A1)
     D03661  Dazmegrel (USAN/INN)
Other DBs
CAS: 76894-77-4
PubChem: 17397757
ChEMBL: CHEMBL283656
LigandBox: D03661
NIKKAJI: J23.271H
KCF data

ATOM        21
            1   C8x C    24.3196  -16.2013
            2   C8x C    24.3196  -14.7991
            3   C8x C    25.5114  -14.0980
            4   C8y C    26.7733  -14.7991
            5   C8y C    26.7733  -16.2013
            6   C8x C    25.5114  -16.9024
            7   N4y N    28.0353  -14.3785
            8   C8y C    28.8766  -15.5002
            9   C8y C    28.0353  -16.6219
            10  C1a C    30.2787  -15.5002
            11  C1b C    28.0353  -18.0219
            12  N4y N    29.2590  -18.7291
            13  C8x C    29.2590  -20.1291
            14  C8x C    30.5905  -20.5618
            15  N5x N    31.4134  -19.4291
            16  C8x C    30.5905  -18.2965
            17  C1b C    28.0353  -12.9785
            18  C1b C    29.2862  -12.2565
            19  C6a C    30.4760  -12.9439
            20  O6a O    31.6664  -12.2568
            21  O6a O    30.4758  -14.3498
BOND        23
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 1
            9     8   9 2
            10    5   9 1
            11    8  10 1
            12    9  11 1
            13   11  12 1
            14   12  13 1
            15   13  14 2
            16   14  15 1
            17   15  16 2
            18   12  16 1
            19    7  17 1
            20   17  18 1
            21   18  19 1
            22   19  20 1
            23   19  21 2

» Japanese version   » Back

DBGET integrated database retrieval system