KEGG   DRUG: Dazoxiben hydrochloride
Entry
D03663                      Drug                                   

Name
Dazoxiben hydrochloride (USAN)
Formula
C12H12N2O3. HCl
Exact mass
268.0615
Mol weight
268.6962
Structure
Class
Cardiovascular agent
 DG01712  Antiplatelet agent
  DG01516  Thromboxane A2 synthase inhibitor
 DG01950  Antithrombotic agent
  DG01712  Antiplatelet agent
   DG01516  Thromboxane A2 synthase inhibitor
 DG01516  Thromboxane A2 synthase inhibitor
Efficacy
Antithrombotic, Thromboxane A2 (TXA2) synthase inhibitor
Target
TBXAS1 (CYP5A1) [HSA:6916] [KO:K01832]
  Pathway
hsa00590  Arachidonic acid metabolism
hsa04611  Platelet activation
Interaction
Brite
Target-based classification of drugs [BR:br08310]
 Enzymes
  Isomerases (EC5)
   Thromboxane-A synthase
    TBXAS1 (CYP5A1)
     D03663  Dazoxiben hydrochloride (USAN)
Other DBs
CAS: 74226-22-5
PubChem: 17397759
ChEMBL: CHEMBL537708
DrugBank: DB03052
LigandBox: D03663
NIKKAJI: J358.650B
KCF data

ATOM        18
            1   X   Cl   36.5700  -14.9846
            2   C8x C    24.8500  -14.1400
            3   C8y C    24.8500  -15.5400
            4   C8x C    26.0624  -16.2400
            5   C8x C    27.2749  -15.5400
            6   C8y C    27.2749  -14.1400
            7   C8x C    26.0624  -13.4400
            8   C6a C    23.6376  -16.2400
            9   O6a O    22.4421  -15.5496
            10  O6a O    23.6375  -17.6398
            11  O2a O    28.5060  -13.4290
            12  C1b C    29.7112  -14.1247
            13  C1b C    30.8935  -13.4419
            14  N4y N    32.0875  -14.1312
            15  C8x C    32.0875  -15.5312
            16  C8x C    33.4190  -15.9638
            17  N5x N    34.2419  -14.8312
            18  C8x C    33.4190  -13.6986
BOND        18
            1     2   3 2
            2     3   4 1
            3     4   5 2
            4     5   6 1
            5     6   7 2
            6     2   7 1
            7     3   8 1
            8     8   9 1
            9     8  10 2
            10    6  11 1
            11   11  12 1
            12   12  13 1
            13   13  14 1
            14   14  15 1
            15   15  16 2
            16   16  17 1
            17   17  18 2
            18   14  18 1

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