KEGG   DRUG: Detomidine hydrochlorideHelp
Entry
D03702                      Drug                                   

Name
Detomidine hydrochloride (USAN)
Formula
C12H14N2. HCl
Exact mass
222.0924
Mol weight
222.7139
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Cardiovascular agent
 DG01456  Adrenergic receptor agonist
  DG01450  alpha-Adrenergic receptor agonist
   DG01449  alpha2-Adrenergic receptor agonist
    DG01655  alpha2-adrenergic receptor specific agonist
Remark
Chemical structure group: DG01318
Efficacy
Analgesic (veterinary), Sedative-hypnotic, alpha2-Adrenergic receptor agonist
Target
ADRA2 [HSA:150 151 152] [KO:K04138 K04139 K04140]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    ADRA2
     D03702  Detomidine hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 90038-01-0
PubChem: 17397794
ChEMBL: CHEMBL2106210
LigandBox: D03702
KCF data Show

ATOM        15
            1   C8y C     4.3400  -19.4600
            2   C8x C     4.3400  -20.8600
            3   C8x C     5.5524  -21.5600
            4   C8x C     6.7649  -20.8600
            5   C8y C     6.7649  -19.4600
            6   C8y C     5.5524  -18.7600
            7   C8x C     9.1897  -20.8600
            8   C8y C     9.1897  -19.4600
            9   C1b C     7.9773  -18.7600
            10  N4x N    10.5212  -21.2926
            11  C8x C    11.3441  -20.1600
            12  N5x N    10.5212  -19.0274
            13  C1a C     5.5524  -17.3602
            14  C1a C     3.1276  -18.7600
            15  X   Cl   13.5100  -20.3700
BOND        15
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     7   8 2
            8     8   9 1
            9     5   9 1
            10    7  10 1
            11   10  11 1
            12   11  12 2
            13    8  12 1
            14    6  13 1
            15    1  14 1

» Japanese version   » Back

DBGET integrated database retrieval system