| Entry |
|
|---|
| Name |
Ecopipam hydrochloride (USAN) |
|---|
| Formula |
C19H20ClNO. HCl
|
|---|
| Exact mass |
349.1000
|
|---|
| Mol weight |
350.28
|
|---|
| Structure |
|
|---|
| Class |
Neuropsychiatric agent
DG01478 Dopamine antagonist
|
|---|
| Efficacy |
Dopamine receptor antagonist |
|---|
| Comment |
Treatment of addiction disorders (selective dopamine receptor D1/D5 antagonist)
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
D03937 Ecopipam hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD1
D03937 Ecopipam hydrochloride (USAN)
DRD5
D03937 Ecopipam hydrochloride (USAN)
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 23
1 C1y C 41.0797 -23.6232
2 N1y N 42.3245 -22.9985
3 C1x C 43.5969 -23.5763
4 C1x C 43.9343 -24.9217
5 C1y C 40.7976 -25.0004
6 C8y C 43.0932 -26.0401
7 C8y C 41.6952 -26.0712
8 C1x C 40.0346 -22.6962
9 C1x C 38.7093 -23.1377
10 C8y C 38.4273 -24.5150
11 C8y C 39.4722 -25.4419
12 C8x C 40.9967 -27.2809
13 C8y C 41.6952 -28.4907
14 C8y C 43.0921 -28.4907
15 C8x C 43.7905 -27.2809
16 O1a O 40.9816 -29.7271
17 X Cl 43.7950 -29.7078
18 C8x C 37.1020 -24.9565
19 C8x C 36.8217 -26.3251
20 C8x C 37.8667 -27.2520
21 C8x C 39.1921 -26.8105
22 C1a C 42.3674 -21.5990
23 X Cl 47.9627 -25.0181
BOND 25
1 3 4 1
2 1 5 1
3 4 6 1
4 2 3 1
5 5 7 1
6 1 2 1
7 6 7 1
8 1 8 1
9 8 9 1
10 9 10 1
11 10 11 1
12 5 11 1
13 7 12 2
14 12 13 1
15 13 14 2
16 14 15 1
17 15 6 2
18 13 16 1
19 14 17 1
20 10 18 2
21 18 19 1
22 19 20 2
23 20 21 1
24 11 21 2
25 2 22 1
|
|---|
