| Entry |
|
|---|
| Name |
Levoleucovorin calcium (USAN);
Calcium levofolinate (INN);
Levofolinate calcium (JAN);
Fusilev (TN);
Isovorin (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C20H21N7O7. Ca
|
|---|
| Exact mass |
511.1128
|
|---|
| Mol weight |
511.5014
|
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| Structure |
|
|---|
| Simcomp |
|
|---|
| Remark |
| Therapeutic category: | 3929 |
| Product (DG03003): | D04715<JP/US> D11394<US> D11555<US> |
|
|---|
| Efficacy |
Antidote (antifolate), Antineoplastic (enhancer) |
|---|
| Disease |
|
|---|
| Comment |
Tetrahydrofolic acid [CPD: C00101] derivative
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
V VARIOUS
V03 ALL OTHER THERAPEUTIC PRODUCTS
V03A ALL OTHER THERAPEUTIC PRODUCTS
V03AF Detoxifying agents for antineoplastic treatment
V03AF04 Calcium levofolinate
D04715 Levoleucovorin calcium (USAN) <JP/US>
USP drug classification [BR:br08302]
Antineoplastics
Treatment Adjuncts
Levoleucovorin
D04715 Levoleucovorin calcium (USAN)
Antineoplastics, Other
Levoleucovorin
D04715 Levoleucovorin calcium (USAN)
Therapeutic category of drugs in Japan [BR:br08301]
3 Agents affecting metabolism
39 Other agents affecting metabolism
392 Antidotes
3929 Others
D04715 Levoleucovorin calcium (USAN); Calcium levofolinate (INN); Levofolinate calcium (JAN)
|
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| Other DBs |
|
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| KCF data |
ATOM 35
1 C1c C 24.1500 -14.7700
2 C1b C 25.3400 -15.4700
3 C6a C 24.1500 -13.3700
4 C8y C 9.6600 -18.9700
5 N5x N 9.6600 -17.5700
6 C8y C 10.8500 -16.8700
7 C8y C 12.0400 -17.5700
8 C8y C 12.0400 -18.9700
9 N4x N 10.8500 -19.6700
10 N1y N 13.3000 -16.8700
11 C1y C 14.4900 -17.5700
12 C1x C 14.4900 -18.9700
13 N1x N 13.3000 -19.6700
14 O5x O 10.8500 -15.4700
15 C4a C 13.3000 -15.4700
16 O4a O 14.4900 -14.7700
17 N1a N 8.4000 -19.6700
18 C1b C 15.6800 -16.8700
19 N1b N 16.8700 -17.5700
20 C8y C 18.0600 -16.8700
21 C8x C 18.0600 -15.4700
22 C8x C 19.3200 -14.7700
23 C8y C 20.5100 -15.4700
24 C8x C 20.5100 -16.8700
25 C8x C 19.3200 -17.5700
26 C5a C 21.7700 -14.7700
27 N1b N 22.9600 -15.4700
28 O5a O 21.7700 -13.3700
29 O6a O 25.3400 -12.6700 #-
30 O6a O 22.8900 -12.6700
31 C1b C 26.5300 -14.7700
32 C6a C 27.7200 -15.4700
33 O6a O 28.9100 -14.7700 #-
34 O6a O 27.7200 -16.8700
35 Z Ca 28.0700 -12.6700 #2+
BOND 36
1 1 2 1
2 1 3 1 #Down
3 4 5 2
4 5 6 1
5 6 7 1
6 7 8 2
7 8 9 1
8 4 9 1
9 7 10 1
10 10 11 1
11 11 12 1
12 12 13 1
13 8 13 1
14 6 14 2
15 10 15 1
16 15 16 2
17 4 17 1
18 11 18 1
19 18 19 1
20 19 20 1
21 20 21 2
22 21 22 1
23 22 23 2
24 23 24 1
25 24 25 2
26 20 25 1
27 23 26 1
28 26 27 1
29 26 28 2
30 1 27 1
31 3 29 1
32 3 30 2
33 2 31 1
34 31 32 1
35 32 33 1
36 32 34 2
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