KEGG   DRUG: Medetomidine hydrochlorideHelp
Entry
D04883                      Drug                                   

Name
Medetomidine hydrochloride (USAN)
Formula
C13H16N2. HCl
Exact mass
236.108
Mol weight
236.7405
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Cardiovascular agent
 DG01456  Adrenergic receptor agonist
  DG01450  alpha-Adrenergic receptor agonist
   DG01449  alpha2-Adrenergic receptor agonist
    DG01655  alpha2-adrenergic receptor specific agonist
Remark
Chemical structure group: DG01320
Efficacy
Analgesic (veterinary), Sedative (veterinary), alpha2-Adrenergic receptor agonist
Target
ADRA2 [HSA:150 151 152] [KO:K04138 K04139 K04140]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    ADRA2
     D04883  Medetomidine hydrochloride (USAN)
Animal drugs in Japan [BR:br08331]
 91  Agents affecting nervous system
  912  Hypnotics and sedatives
   9129  Other hypnotics and sedatives
    D04883  Medetomidine hydrochloride
BRITE hierarchy
Other DBs
CAS: 86347-15-1
PubChem: 47206647
ChEBI: 48556
ChEMBL: CHEMBL537161
LigandBox: D04883
NIKKAJI: J346.513F
KCF data Show

ATOM        16
            1   X   Cl   37.9596  -17.8822
            2   C8y C    28.4900  -17.1500
            3   C8x C    28.4900  -18.5500
            4   C8x C    29.7024  -19.2500
            5   C8x C    30.9149  -18.5500
            6   C8y C    30.9149  -17.1500
            7   C8y C    29.7024  -16.4500
            8   C8x C    33.3397  -18.5500
            9   C8y C    33.3397  -17.1500
            10  C1c C    32.1273  -16.4500
            11  N4x N    34.6712  -18.9826
            12  C8x C    35.4941  -17.8500
            13  N5x N    34.6712  -16.7174
            14  C1a C    32.1273  -15.0500
            15  C1a C    29.7024  -15.0502
            16  C1a C    27.2776  -16.4500
BOND        16
            1     2   3 2
            2     3   4 1
            3     4   5 2
            4     5   6 1
            5     6   7 2
            6     2   7 1
            7     8   9 2
            8     9  10 1
            9     6  10 1
            10    8  11 1
            11   11  12 1
            12   12  13 2
            13    9  13 1
            14   10  14 1
            15    7  15 1
            16    2  16 1

» Japanese version   » Back

DBGET integrated database retrieval system