| Entry |
|
|---|
| Name |
Metyrapone tartrate (USAN);
Metopirone ditartrate (TN) |
|---|
| Formula |
C14H14N2O. (C4H6O6)2
|
|---|
| Exact mass |
526.1435
|
|---|
| Mol weight |
526.4474
|
|---|
| Structure |
|
|---|
| Remark |
| Product (DG01166): | D00410<JP/US> |
|
|---|
| Efficacy |
Diagnostic aid (pituitary function determination) |
|---|
| Comment |
corticosteroid synthesis inhibitor
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
V VARIOUS
V04 DIAGNOSTIC AGENTS
V04C OTHER DIAGNOSTIC AGENTS
V04CD Tests for pituitary function
V04CD01 Metyrapone
D05019 Metyrapone tartrate (USAN)
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Cytochrome P450
CYP11B1
D05019 Metyrapone tartrate (USAN)
|
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| Other DBs |
|
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| KCF data |
ATOM 37
1 C8x C 34.3843 -23.9561
2 N5x N 34.3843 -25.3573
3 C8x C 35.5978 -26.0579
4 C8y C 36.8113 -25.3573
5 C8x C 36.8113 -23.9561
6 C8x C 35.5978 -23.2554
7 C5a C 38.0435 -26.0690
8 C1d C 39.2498 -25.3726
9 C8y C 40.4332 -26.0560
10 O5a O 38.0432 -27.4591
11 C8x C 40.4331 -27.4590
12 C8x C 41.6464 -28.1597
13 C8x C 42.8600 -27.4592
14 N5x N 42.8601 -26.0562
15 C8x C 41.6466 -25.3555
16 C1a C 40.2401 -24.3823
17 C1a C 38.2596 -24.3823
18 C1c C 49.5390 -26.3788
19 C1c C 50.7274 -25.6798
20 C6a C 48.2806 -25.6798
21 O1a O 49.5390 -27.7771
22 C6a C 51.9159 -26.3788
23 O1a O 50.7274 -24.2815
24 O6a O 47.0921 -26.3788
25 O6a O 48.2806 -24.2815
26 O6a O 53.1744 -25.6798
27 O6a O 51.9159 -27.7771
28 C1c C 49.5390 -26.3788
29 C1c C 50.7274 -25.6798
30 C6a C 51.9159 -26.3788
31 O6a O 53.1744 -25.6798
32 O6a O 51.9159 -27.7771
33 O1a O 50.7274 -24.2815
34 C6a C 48.2806 -25.6798
35 O6a O 47.0921 -26.3788
36 O6a O 48.2806 -24.2815
37 O1a O 49.5390 -27.7771
BOND 36
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 1
10 7 10 2
11 9 11 2
12 11 12 1
13 12 13 2
14 13 14 1
15 14 15 2
16 9 15 1
17 8 16 1
18 8 17 1
19 18 19 1
20 18 20 1
21 18 21 1 #Up
22 19 22 1
23 19 23 1 #Up
24 20 24 1
25 20 25 2
26 22 26 1
27 22 27 2
28 28 29 1
29 28 34 1
30 28 37 1 #Up
31 29 30 1
32 29 33 1 #Up
33 34 35 1
34 34 36 2
35 30 31 1
36 30 32 2
BRACKET 1 45.2200 -28.7000 45.2200 -23.0300
1 55.1600 -23.0300 55.1600 -28.7000
1 2
ORIGINAL 1 18 19 22 26 27 23 20 24 25 21
REPEAT 1 28 29 30 31 32 33 34 35 36 37
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