KEGG   DRUG: Phenylpropanolamine polistirexHelp
Entry
D05466                      Drug                                   

Name
Phenylpropanolamine polistirex (USAN)
Class
Cardiovascular agent
 DG01456  Adrenergic receptor agonist
  DG01450  alpha-Adrenergic receptor agonist
   DG01448  alpha1-Adrenergic receptor agonist
   DG01449  alpha2-Adrenergic receptor agonist
  DG01455  beta-Adrenergic receptor agonist
   DG01451  beta1-Adrenergic receptor agonist
   DG01452  beta2-Adrenergic receptor agonist
   DG01453  beta3-Adrenergic receptor agonist
Metabolizing enzyme inhibitor
 DG01634  CYP1A2 inhibitor
Remark
ATC code: R01BA01
Chemical structure group: DG01041
Efficacy
Vasoconstrictor, Adrenergic receptor agonist
Target
ADRA1 [HSA:148 147 146] [KO:K04135 K04136 K04137]
ADRA2 [HSA:150 151 152] [KO:K04138 K04139 K04140]
ADRB [HSA:153 154 155] [KO:K04141 K04142 K04143]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04270  Vascular smooth muscle contraction
Interaction
CYP inhibition: CYP1A2 [HSA:1544]
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 R RESPIRATORY SYSTEM
  R01 NASAL PREPARATIONS
   R01B NASAL DECONGESTANTS FOR SYSTEMIC USE
    R01BA Sympathomimetics
     R01BA01 Phenylpropanolamine
      D05466  Phenylpropanolamine polistirex (USAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    ADRA1
     D05466  Phenylpropanolamine polistirex (USAN)
    ADRA2
     D05466  Phenylpropanolamine polistirex (USAN)
    ADRB
     D05466  Phenylpropanolamine polistirex (USAN)
BRITE hierarchy
Other DBs
PubChem: 47207135
DrugBank: DB00397

» Japanese version   » Back

DBGET integrated database retrieval system