KEGG   DRUG: RuplizumabHelp
Entry
D05777                      Drug                                   

Name
Ruplizumab (USAN/INN)
Efficacy
Antithrombocytopenia, Immunosuppressant, Anti-CD154 antibody, Anti-CD40 ligand antibody
Comment
Monoclonal antibody
Treatment of immune thrombocytopenic purpura and systemic lupus erythematosus
Target
TNFSF5 (CD154) [HSA:959] [KO:K03161]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04514  Cell adhesion molecules (CAMs)
hsa04660  T cell receptor signaling pathway
Brite
Target-based classification of drugs [BR:br08310]
 Cytokines and receptors
  Cytokines
   Tumor necrosis factors
    TNFSF5 (CD154)
     D05777  Ruplizumab (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 220651-94-5
PubChem: 47207438

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