KEGG   DRUG: Tilidine hydrochlorideHelp
Entry
D06147                      Drug                                   

Name
Tilidine hydrochloride (USAN);
Valoron (TN)
Formula
C17H23NO2. HCl
Exact mass
309.1496
Mol weight
309.831
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG01564  Opioid receptor agonist
  DG01563  mu-Opioid receptor agonist
Analgesic
 DG01984  Opioid analgesics
Remark
ATC code: N02AX01
Chemical structure group: DG00823
Efficacy
Analgesic, Opioid receptor agonist
Target
OPRM1 [HSA:4988] [KO:K04215]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N02 ANALGESICS
   N02A OPIOIDS
    N02AX Other opioids
     N02AX01 Tilidine
      D06147  Tilidine hydrochloride (USAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Opioid
    OPRM1
     D06147  Tilidine hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 27107-79-5
PubChem: 47207805
LigandBox: D06147
NIKKAJI: J410.859K
KCF data Show

ATOM        21
            1   C2x C    18.9700  -15.4000
            2   C2x C    18.9700  -16.8000
            3   C1x C    20.1824  -17.5000
            4   C1x C    21.3949  -16.8000
            5   C1z C    21.3949  -15.4000
            6   C1y C    20.1824  -14.7000
            7   C8y C    23.4660  -13.9190
            8   C8x C    24.6712  -14.6147
            9   C8x C    25.8835  -13.9146
            10  C8x C    25.8835  -12.5146
            11  C8x C    24.6783  -11.8189
            12  C8x C    23.4659  -12.5190
            13  N1c N    20.1824  -13.3002
            14  C1a C    18.9532  -12.5903
            15  C1a C    21.3780  -12.6098
            16  C7a C    22.6073  -16.1000
            17  O7a O    22.6110  -17.5000
            18  O6a O    23.8208  -15.3972
            19  C1b C    23.8246  -18.1963
            20  C1a C    23.8284  -19.5997
            21  X   Cl   27.7200  -16.8700
BOND        21
            1     1   2 2
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     5   7 1 #Up
            8     7   8 2
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12   11  12 2
            13    7  12 1
            14    6  13 1 #Up
            15   13  14 1
            16   13  15 1
            17    5  16 1
            18   16  17 1
            19   16  18 2
            20   17  19 1
            21   19  20 1

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