KEGG   DRUG: Yohimbine hydrochlorideHelp
Entry
D06671                      Drug                                   

Name
Yohimbine hydrochloride (USP)
Formula
C21H26N2O3. HCl
Exact mass
390.171
Mol weight
390.9037
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Cardiovascular agent
 DG01466  Adrenergic receptor antagonist
  DG01465  alpha-Adrenergic receptor antagonist
   DG01460  alpha2-Adrenergic receptor antagonist
Remark
ATC code: G04BE04
Chemical structure group: DG00485
Efficacy
alpha2-Adrenergic receptor antagonist
Target
ADRA2 [HSA:150 151 152] [KO:K04138 K04139 K04140]
  Pathway
hsa04022  cGMP-PKG signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 G GENITO URINARY SYSTEM AND SEX HORMONES
  G04 UROLOGICALS
   G04B UROLOGICALS
    G04BE Drugs used in erectile dysfunction
     G04BE04 Yohimbin
      D06671  Yohimbine hydrochloride (USP)
Classification of Japanese OTC drugs [BR:br08313]
 Agents for  urogenital organs and anus
  31 Other drugs for  urogenital organs and anus
   D06671  Yohimbine hydrochloride (USP)
Risk category of Japanese OTC drugs [BR:br08312]
 Drugs requiring guidance
  Powerful drugs
   Yohimbine
    D06671  Yohimbine hydrochloride (USP)
 First-class OTC drugs
  Inorganic and organic chemicals
   Yohimbine
    D06671  Yohimbine hydrochloride (USP)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    ADRA2
     D06671  Yohimbine hydrochloride (USP)
BRITE hierarchy
Other DBs
CAS: 65-19-0
PubChem: 47208322
ChEMBL: CHEMBL537669
LigandBox: D06671
NIKKAJI: J237.516H
KCF data Show

ATOM        27
            1   C8x C    21.2100  -16.4500
            2   C8x C    21.2100  -17.7800
            3   C8x C    22.4700  -18.4800
            4   C8x C    22.4000  -15.6800
            5   C8y C    23.5900  -16.3800
            6   C8y C    23.5900  -17.7100
            7   C1x C    26.8100  -14.3500
            8   C1x C    25.4100  -14.5600
            9   N1y N    27.6500  -15.4700
            10  C1y C    27.0900  -16.7300
            11  C1x C    28.0000  -17.8500
            12  C1x C    28.9800  -15.2600
            13  C1y C    29.8900  -16.3800
            14  C1y C    29.3300  -17.6400
            15  C1y C    30.1700  -18.6900
            16  C1y C    31.5700  -18.5500
            17  C1x C    32.0600  -17.2200
            18  C1x C    31.2200  -16.1700
            19  C8y C    25.7600  -16.9400
            20  C8y C    24.9200  -15.8900
            21  N4x N    24.9900  -18.1300
            22  C7a C    29.6271  -19.9805
            23  O6a O    28.2255  -20.1575
            24  O7a O    30.4526  -21.0681
            25  C1a C    31.8388  -20.8931
            26  O1a O    32.4270  -19.6571
            27  X   Cl   34.9300  -17.4300
BOND        30
            1     1   2 1
            2    19  10 1
            3     9   7 1
            4     7   8 1
            5    13  14 1
            6    14  15 1
            7    15  16 1
            8    16  17 1
            9    17  18 1
            10   18  13 1
            11    8  20 1
            12    2   3 2
            13    3   6 1
            14    5   4 1
            15   19  20 2
            16   20   5 1
            17    6  21 1
            18   21  19 1
            19    4   1 2
            20    9  10 1
            21   10  11 1
            22   11  14 1
            23   13  12 1
            24   12   9 1
            25    5   6 2
            26   15  22 1 #Down
            27   22  23 2
            28   22  24 1
            29   24  25 1
            30   16  26 1 #Down

» Japanese version   » Back

DBGET integrated database retrieval system