KEGG   DRUG: Triflusal
Entry
D07142                      Drug                                   

Name
Triflusal (INN)
Formula
C10H7F3O4
Exact mass
248.0296
Mol weight
248.1554
Structure
Class
Cardiovascular agent
 DG01712  Antiplatelet agent
 DG01950  Antithrombotic agent
  DG01712  Antiplatelet agent
Remark
ATC code: B01AC18
Efficacy
Platelet aggregation inhibitor, COX-1 inhibitor
Comment
Salicylic acid derivative
Target
PTGS1 (COX1) [HSA:5742] [KO:K00509]
  Pathway
hsa00590  Arachidonic acid metabolism
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 B BLOOD AND BLOOD FORMING ORGANS
  B01 ANTITHROMBOTIC AGENTS
   B01A ANTITHROMBOTIC AGENTS
    B01AC Platelet aggregation inhibitors excl. heparin
     B01AC18 Triflusal
      D07142  Triflusal (INN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases (EC1)
   Prostaglandin synthase
    PTGS1 (COX1)
     D07142  Triflusal (INN)
Other DBs
CAS: 322-79-2
PubChem: 51091481
ChEMBL: CHEMBL1332032
LigandBox: D07142
NIKKAJI: J5.672C
KCF data

ATOM        17
            1   C8x C    21.1230  -16.8540
            2   C8x C    21.1230  -18.2525
            3   C8y C    22.3342  -18.9518
            4   C8x C    23.5454  -18.2525
            5   C8y C    23.5454  -16.8540
            6   C8y C    22.3342  -16.1547
            7   O7a O    24.7817  -16.1547
            8   C7a C    25.9929  -16.8540
            9   O6a O    27.2228  -16.1437
            10  C1a C    25.9930  -18.2523
            11  C6a C    22.3231  -14.7561
            12  O6a O    21.1175  -14.0471
            13  O6a O    23.5259  -14.0617
            14  C1d C    22.3342  -20.3502
            15  X   F    22.2951  -21.7391
            16  X   F    20.9342  -20.3502
            17  X   F    23.7342  -20.3502
BOND        17
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     8   9 2
            10    8  10 1
            11    6  11 1
            12   11  12 1
            13   11  13 2
            14    3  14 1
            15   14  15 1
            16   14  16 1
            17   14  17 1

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