| Entry |
|
|---|
| Name |
Loxoprofen (INN) |
|---|
| Formula |
C15H18O3
|
|---|
| Exact mass |
246.1256
|
|---|
| Mol weight |
246.3016
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01908 Anti-inflammatory drug, propionic acid derivatives
|
|---|
| Remark |
| Product (DG01251): | D01709<JP> |
|
|---|
| Efficacy |
Analgesic, Anti-inflammatory, Antipyretic, COX inhibitor |
|---|
| Comment |
Propionic acid derivative
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
M MUSCULO-SKELETAL SYSTEM
M02 TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
M02A TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
M02AA Antiinflammatory preparations, non-steroids for topical use
M02AA31 Loxoprofen
D08149 Loxoprofen (INN)
Risk category of Japanese OTC drugs [BR:br08312]
First-class OTC drugs
Inorganic and organic chemicals
Loxoprofen
D08149 Loxoprofen (INN)
Second-class OTC drugs
Inorganic and organic chemicals
Loxoprofen
D08149 Loxoprofen (INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01908 Anti-inflammatory drug, propionic acid derivatives
DG01251 Loxoprofen
D08149 Loxoprofen
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Prostaglandin synthase
PTGS1 (COX1)
D08149 Loxoprofen (INN)
PTGS2 (COX2)
D08149 Loxoprofen (INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01908 Anti-inflammatory drug, propionic acid derivatives
DG01251 Loxoprofen
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 18
1 C8y C 22.6800 -18.8300
2 C8x C 23.8700 -19.5300
3 C8x C 25.0600 -18.8300
4 C8y C 25.0600 -17.4300
5 C8x C 23.8700 -16.7300
6 C8x C 22.6800 -17.4300
7 C1c C 26.3200 -16.7300
8 C6a C 27.5100 -17.4300
9 C1a C 26.3200 -15.3300
10 O6a O 28.7700 -16.7300
11 O6a O 27.5100 -18.7600
12 C1x C 20.2300 -17.4300
13 C1y C 20.2300 -18.8300
14 C1b C 21.4900 -19.5300
15 C1x C 18.9000 -16.9400
16 C1x C 18.0600 -18.1300
17 C5x C 18.9000 -19.2500
18 O5x O 18.4800 -20.5800
BOND 19
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 6 1 1
7 4 7 1
8 7 8 1
9 7 9 1
10 8 10 1
11 8 11 2
12 12 13 1
13 13 14 1
14 1 14 1
15 12 15 1
16 15 16 1
17 16 17 1
18 13 17 1
19 17 18 2
|
|---|
