| Entry |
|
|---|
| Name |
Metixene (INN) |
|---|
| Formula |
C20H23NS
|
|---|
| Exact mass |
309.1551
|
|---|
| Mol weight |
309.4683
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
|
|---|
| Remark |
|
|---|
| Efficacy |
Antiparkinsonian, Muscarinic acetylcholine receptor antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N04 ANTI-PARKINSON DRUGS
N04A ANTICHOLINERGIC AGENTS
N04AA Tertiary amines
N04AA03 Metixene
D08209 Metixene (INN)
Risk category of Japanese OTC drugs [BR:br08312]
Second-class OTC drugs
Inorganic and organic chemicals
Metixene
D08209 Metixene (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
DG00853 Metixene
D08209 Metixene
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Acetylcholine (muscarinic)
CHRM
D08209 Metixene (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
DG00853 Metixene
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 22
1 C8x C 19.0400 -19.2500
2 C8x C 19.0400 -20.6500
3 C8x C 20.3000 -21.4200
4 C8x C 20.3000 -18.5500
5 C8y C 21.4900 -19.2500
6 C8y C 21.4900 -20.6500
7 S2x S 22.6800 -21.4200
8 C1y C 22.6800 -18.6200
9 C8y C 23.9400 -19.3200
10 C8y C 23.9400 -20.7200
11 C8x C 25.1300 -21.4200
12 C8x C 26.3200 -20.7200
13 C8x C 26.3200 -19.3200
14 C8x C 25.1300 -18.6200
15 C1b C 22.6800 -17.2200
16 C1y C 23.9400 -16.5200
17 C1x C 25.1300 -17.2200
18 N1y N 26.3200 -16.5200
19 C1x C 26.3200 -15.1200
20 C1x C 25.1300 -14.4200
21 C1x C 23.9400 -15.1200
22 C1a C 27.5800 -17.2200
BOND 25
1 4 1 1
2 9 10 2
3 10 11 1
4 11 12 2
5 12 13 1
6 13 14 2
7 14 9 1
8 8 15 1
9 1 2 2
10 15 16 1
11 5 6 1
12 6 7 1
13 7 10 1
14 9 8 1
15 8 5 1
16 16 17 1
17 17 18 1
18 18 19 1
19 19 20 1
20 20 21 1
21 21 16 1
22 2 3 1
23 18 22 1
24 3 6 2
25 5 4 2
|
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