| Entry |
|
|---|
| Name |
Moxisylyte (INN);
Carlytene (TN) |
|---|
| Formula |
C16H25NO3
|
|---|
| Exact mass |
279.1834
|
|---|
| Mol weight |
279.3746
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01457 alpha1-Adrenergic receptor antagonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Vasodilator (peripheral), alpha1-Adrenergic receptor antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04270 | Vascular smooth muscle contraction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C04 PERIPHERAL VASODILATORS
C04A PERIPHERAL VASODILATORS
C04AX Other peripheral vasodilators
C04AX10 Moxisylyte
D08239 Moxisylyte (INN)
G GENITO URINARY SYSTEM AND SEX HORMONES
G04 UROLOGICALS
G04B UROLOGICALS
G04BE Drugs used in erectile dysfunction
G04BE06 Moxisylyte
D08239 Moxisylyte (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01457 alpha1-Adrenergic receptor antagonist
DG00287 Moxisylyte
D08239 Moxisylyte
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA1
D08239 Moxisylyte (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01457 alpha1-Adrenergic receptor antagonist
DG00287 Moxisylyte
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 20
1 C8y C 24.1500 -18.2700
2 C8y C 22.9600 -18.9700
3 C8x C 24.1500 -16.8700
4 O2a O 25.3400 -18.9700
5 C8x C 21.7000 -18.2700
6 C1c C 22.9600 -20.3700
7 C8y C 22.9600 -16.1700
8 C1b C 26.6000 -18.2700
9 C8y C 21.7000 -16.8700
10 C1a C 22.9600 -14.7700
11 C1b C 27.7900 -18.9700
12 O7a O 20.5100 -16.1700
13 N1c N 29.0500 -18.2700
14 C7a C 19.3200 -16.8700
15 C1a C 18.1300 -16.1700
16 O6a O 19.3200 -18.2700
17 C1a C 29.0500 -16.8700
18 C1a C 30.2400 -18.9700
19 C1a C 21.7700 -21.0700
20 C1a C 24.1500 -21.0700
BOND 20
1 2 5 1
2 2 6 1
3 3 7 2
4 4 8 1
5 5 9 2
6 7 10 1
7 8 11 1
8 9 12 1
9 11 13 1
10 12 14 1
11 14 15 1
12 14 16 2
13 7 9 1
14 13 17 1
15 13 18 1
16 1 2 2
17 6 19 1
18 1 3 1
19 6 20 1
20 1 4 1
|
|---|
