KEGG   DRUG: Ozagrel
Entry
D08327                      Drug                                   

Name
Ozagrel (INN);
Cataclot (TN)
Formula
C13H12N2O2
Exact mass
228.0899
Mol weight
228.2466
Structure
Simcomp
Class
Cardiovascular agent
 DG01712  Antiplatelet agent
  DG01516  Thromboxane A2 synthase inhibitor
 DG01950  Antithrombotic agent
  DG01712  Antiplatelet agent
   DG01516  Thromboxane A2 synthase inhibitor
 DG01516  Thromboxane A2 synthase inhibitor
Remark
Chemical structure group: DG01256
Product (DG01256): D01683<JP> D01684<JP>
Efficacy
Anticoagulant, Platelet aggregation inhibitor, Thromboxane A2 (TXA2) synthase inhibitor
Target
TBXAS1 (CYP5A1) [HSA:6916] [KO:K01832]
  Pathway
hsa00590  Arachidonic acid metabolism
hsa04611  Platelet activation
Interaction
Structure map
map07034  Eicosanoids
map07049  Antithrombosis agents
Brite
Target-based classification of drugs [BR:br08310]
 Enzymes
  Isomerases (EC5)
   Thromboxane-A synthase
    TBXAS1 (CYP5A1)
     D08327  Ozagrel (INN)
Other DBs
CAS: 82571-53-7
PubChem: 96025014
ChEMBL: CHEMBL11662
LigandBox: D08327
NIKKAJI: J34.702G
KCF data

ATOM        17
            1   N4y N    27.8600  -16.5200
            2   C8x C    28.2800  -17.8500
            3   C8x C    28.9800  -15.6800
            4   C1b C    26.6000  -15.8900
            5   N5x N    29.6800  -17.8500
            6   C8x C    30.1000  -16.5200
            7   C8y C    25.4100  -16.5900
            8   C8x C    25.4100  -17.9900
            9   C8x C    24.1500  -15.8900
            10  C8x C    24.2200  -18.6900
            11  C8x C    23.0300  -16.5900
            12  C8y C    23.0300  -17.9900
            13  C2b C    21.8400  -18.7600
            14  C2b C    20.6500  -18.0600
            15  C6a C    19.3900  -18.7600
            16  O6a O    18.2000  -18.0600
            17  O6a O    19.3900  -20.1600
BOND        18
            1     2   5 2
            2     3   6 2
            3     4   7 1
            4     7   8 2
            5     7   9 1
            6     8  10 1
            7     9  11 2
            8    10  12 2
            9    12  13 1
            10    5   6 1
            11   11  12 1
            12   13  14 2
            13   14  15 1
            14    1   2 1
            15   15  16 1
            16    1   3 1
            17   15  17 2
            18    1   4 1

» Japanese version   » Back

DBGET integrated database retrieval system