| Entry |
|
|---|
| Name |
Pergolide (INN);
Permax (TN) |
|---|
| Formula |
C19H26N2S
|
|---|
| Exact mass |
314.1817
|
|---|
| Mol weight |
314.4881
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
|
|---|
| Remark |
| Product (DG00861): | D00502<JP> |
|
|---|
| Efficacy |
Antiparkinsonian, Dopamine receptor agonist |
|---|
| Comment |
Ergot alkaloid derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N04 ANTI-PARKINSON DRUGS
N04B DOPAMINERGIC AGENTS
N04BC Dopamine agonists
N04BC02 Pergolide
D08339 Pergolide (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01472 Dopamine agonist
DG00861 Pergolide
D08339 Pergolide
DG01964 Ergot alkaloid
DG00861 Pergolide
D08339 Pergolide
DG01967 Antiparkinson agent
DG00861 Pergolide
D08339 Pergolide
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD1
D08339 Pergolide (INN)
DRD2
D08339 Pergolide (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01472 Dopamine agonist
DG00861 Pergolide
DG01964 Ergot alkaloid
DG00861 Pergolide
DG01967 Antiparkinson agent
DG00861 Pergolide
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 22
1 C8y C 21.7700 -20.6500
2 C8y C 21.7700 -19.2500
3 C8y C 22.9600 -21.2800
4 C8y C 20.5800 -21.2800
5 C1y C 22.9600 -18.5500
6 C8x C 20.6500 -18.5500
7 C1x C 24.1500 -20.6500
8 C8x C 22.9600 -22.6800
9 N4x N 20.5800 -22.6800
10 C8x C 19.4600 -20.5800
11 C1y C 24.1500 -19.2500
12 C1x C 22.9600 -17.2200
13 C8x C 19.4600 -19.2500
14 N1y N 25.3400 -18.6200
15 C1y C 24.1500 -16.5200
16 C1x C 25.3400 -17.2200
17 C1b C 26.5300 -19.2500
18 C1b C 24.1500 -15.1900
19 C1b C 27.7200 -18.6200
20 S2a S 25.3400 -14.4900
21 C1a C 28.8400 -19.3200
22 C1a C 25.3400 -13.1600
BOND 25
1 1 2 1
2 1 3 1
3 1 4 2
4 2 5 1
5 2 6 2
6 3 7 1
7 3 8 2
8 4 9 1
9 4 10 1
10 5 11 1
11 5 12 1
12 6 13 1
13 11 14 1
14 12 15 1
15 14 16 1
16 14 17 1
17 15 18 1 #Up
18 17 19 1
19 18 20 1
20 19 21 1
21 20 22 1
22 7 11 1
23 8 9 1
24 10 13 2
25 15 16 1
|
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