KEGG   DRUG: Perphenazine decanoateHelp
Entry
D08341                      Drug                                   

Name
Perphenazine decanoate;
Trilafon dekanoat (TN)
Formula
C31H44ClN3O2S
Exact mass
557.2843
Mol weight
558.218
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG01905  Phenothiazine antipsychotics
 DG01478  Dopamine antagonist
  DG01474  Dopamine D2-receptor antagonist
Remark
ATC code: N05AB03
Chemical structure group: DG00875
Product (DG00875): D00503<JP/US> D02037<JP> D04038<JP> D04965<JP>
Efficacy
Antipsychotic, Neuroleptic, Dopamine D2 receptor antagonist
Comment
Phenothiazine derivative
Target
DRD2 [HSA:1813] [KO:K04145]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04728  Dopaminergic synapse
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N05 PSYCHOLEPTICS
   N05A ANTIPSYCHOTICS
    N05AB Phenothiazines with piperazine structure
     N05AB03 Perphenazine
      D08341  Perphenazine decanoate
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Dopamine
    DRD2
     D08341  Perphenazine decanoate
BRITE hierarchy
Other DBs
CAS: 61120-81-8
PubChem: 96025028
LigandBox: D08341
NIKKAJI: J268.401B
KCF data Show

ATOM        38
            1   C8x C    17.5700  -19.3200
            2   C8x C    17.5700  -20.7900
            3   C8x C    18.7600  -21.4900
            4   C8y C    19.9500  -20.7900
            5   C8y C    19.9500  -19.3200
            6   C8x C    18.7600  -18.6200
            7   S2x S    21.2100  -21.4900
            8   C8y C    22.4000  -20.7900
            9   C8y C    22.4000  -19.3200
            10  N4y N    21.2100  -18.6200
            11  C8x C    23.5900  -21.4900
            12  C8x C    24.8500  -20.7900
            13  C8y C    24.8500  -19.3200
            14  C8x C    23.5900  -18.6200
            15  C1b C    21.2100  -17.2200
            16  C1b C    22.4000  -16.5200
            17  C1b C    23.5900  -17.2200
            18  N1y N    24.7800  -16.5200
            19  C1x C    25.9700  -17.2200
            20  C1x C    27.2300  -16.5200
            21  N1y N    27.2300  -15.1200
            22  C1x C    26.0400  -14.4200
            23  C1x C    24.7800  -15.1200
            24  C1b C    28.4200  -14.4200
            25  C1b C    29.6800  -15.1200
            26  O7a O    30.8000  -14.4200
            27  X   Cl   26.0400  -18.6200
            28  C7a C    32.0124  -15.1200
            29  C1b C    33.2249  -14.4200
            30  C1b C    34.4373  -15.1200
            31  C1b C    35.6497  -14.4200
            32  C1b C    36.8622  -15.1200
            33  C1b C    38.0746  -14.4200
            34  C1b C    39.2870  -15.1200
            35  C1b C    40.4995  -14.4200
            36  C1b C    41.7119  -15.1200
            37  C1a C    42.9244  -14.4200
            38  O6a O    32.0124  -16.5198
BOND        41
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11    5  10 1
            12    8  11 2
            13   11  12 1
            14   12  13 2
            15   13  14 1
            16    9  14 2
            17   10  15 1
            18   15  16 1
            19   16  17 1
            20   17  18 1
            21   18  19 1
            22   19  20 1
            23   20  21 1
            24   21  22 1
            25   22  23 1
            26   18  23 1
            27   21  24 1
            28   24  25 1
            29   25  26 1
            30   13  27 1
            31   26  28 1
            32   28  29 1
            33   29  30 1
            34   30  31 1
            35   31  32 1
            36   32  33 1
            37   33  34 1
            38   34  35 1
            39   35  36 1
            40   36  37 1
            41   28  38 2

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