KEGG   DRUG: TilidineHelp
Entry
D08597                      Drug                                   

Name
Tilidine (INN)
Formula
C17H23NO2
Exact mass
273.1729
Mol weight
273.37
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG01564  Opioid receptor agonist
  DG01563  mu-Opioid receptor agonist
Analgesic
 DG01984  Opioid analgesics
Remark
ATC code: N02AX01
Chemical structure group: DG00823
Efficacy
Analgesic, Opioid receptor agonist
Target
OPRM1 [HSA:4988] [KO:K04215]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N02 ANALGESICS
   N02A OPIOIDS
    N02AX Other opioids
     N02AX01 Tilidine
      D08597  Tilidine (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Opioid
    OPRM1
     D08597  Tilidine (INN)
BRITE hierarchy
Other DBs
CAS: 20380-58-9
PubChem: 96025281
ChEBI: 77823
ChEMBL: CHEMBL2104560
LigandBox: D08597
NIKKAJI: J244.473I
KCF data Show

ATOM        20
            1   C2x C    20.8600  -17.6400
            2   C2x C    20.8600  -18.9700
            3   C1x C    22.0500  -19.6700
            4   C1x C    23.1700  -18.9700
            5   C1z C    23.1700  -17.6400
            6   C1y C    22.0500  -16.9400
            7   C8y C    25.2000  -16.1700
            8   C8x C    26.3200  -16.8700
            9   C8x C    27.5100  -16.1700
            10  C8x C    27.5100  -14.8400
            11  C8x C    26.3200  -14.2100
            12  C8x C    25.2000  -14.8400
            13  N1c N    22.0500  -15.6100
            14  C1a C    20.8600  -14.9100
            15  C1a C    23.1700  -14.9100
            16  C7a C    24.3600  -18.2700
            17  O7a O    24.3600  -19.6700
            18  O6a O    25.5500  -17.6400
            19  C1b C    25.5500  -20.3000
            20  C1a C    25.5500  -21.7000
BOND        21
            1     1   2 2
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     5   7 1 #Up
            8     7   8 2
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12   11  12 2
            13    7  12 1
            14    6  13 1 #Up
            15   13  14 1
            16   13  15 1
            17    5  16 1
            18   16  17 1
            19   16  18 2
            20   17  19 1
            21   19  20 1

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