KEGG   DRUG: Bevasiranib sodiumHelp
Entry
D08874                      Drug                                   

Name
Bevasiranib sodium (USAN)
Formula
C401H463N153Na40O290P40
Exact mass
14218.1598
Mol weight
14224.3593
Efficacy
Aging-related macular degeneration therapeutic agent, Angiogenesis inhibitor
Comment
siRNA inhibitor of Vascular Endothelial Growth Factor (VEGF) production
Treatment of wet age-related macular degeneration
Target
VEGFA [HSA:7422] [KO:K05448] (mRNA)
  Pathway
hsa04370  VEGF signaling pathway
Brite
Target-based classification of drugs [BR:br08310]
 Cytokines and receptors
  Cytokines
   Growth factors (RTK-binding)
    VEGFA
     D08874  Bevasiranib sodium (USAN)
BRITE hierarchy
Other DBs
CAS: 849758-52-7
PubChem: 96025557

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