KEGG   DRUG: Girentuximab
Entry
D09593                      Drug                                   

Name
Girentuximab (USAN/INN)
Formula
C6460H10006N1718O2018S48
Exact mass
145473.9755
Mol weight
145563.9894
Sequence
(Heavy chain)
DVKLVESGGG LVKLGGSLKL SCAASGFTFS NYYMSWVRQT PEKRLELVAA INSDGGITYY
LDTVKGRFTI SRDNAKNTLY LQMSSLKSED TALFYCARHR SGYFSMDYWG QGTSVTVSSA
STKGPSVFPL APSSKSTSGG TAALGCLVKD YFPEPVTVSW NSGALTSGVH TFPAVLQSSG
LYSLSSVVTV PSSSLGTQTY ICNVNHKPSN TKVDKKVEPK SCDKTHTCPP CPAPELLGGP
SVFLFPPKPK DTLMISRTPE VTCVVVDVSH EDPEVKFNWY VDGVEVHNAK TKPREEQYNS
TYRVVSVLTV LHQDWLNGKE YKCKVSNKAL PAPIEKTISK AKGQPREPQV YTLPPSRDEL
TKNQVSLTCL VKGFYPSDIA VEWESNGQPE NNYKTTPPVL DSDGSFFLYS KLTVDKSRWQ
QGNVFSCSVM HEALHNHYTQ KSLSLSPGK
(Light chain)
DIVMTQSQRF MSTTVGDRVS ITCKASQNVV SAVAWYQQKP GQSPKLLIYS ASNRYTGVPD
RFTGSGSGTD FTLTISNMQS EDLADFFCQQ YSNYPWTFGG GTKLEIKRTV AAPSVFIFPP
SDEQLKSGTA SVVCLLNNFY PREAKVQWKV DNALQSGNSQ ESVTEQDSKD STYSLSSTLT
LSKADYEKHK VYACEVTHQG LSSPVTKSFN RGEC
(Disulfide bridge: H22-H96, H146-H202, H263-H323, H369-H427, H228-H'228, H231-H'231, L23-L88, L134-L194, H222-L214)
  Type
Peptide
Efficacy
Antineoplastic, Natural killer cell stimulant
Comment
Monoclonal antibody
Target
CA9 [HSA:768] [KO:K01672]
Brite
Target-based classification of drugs [BR:br08310]
 Enzymes
  Lyases (EC4)
   Aldehyde-lyases
    CA9
     D09593  Girentuximab (USAN/INN)
Other DBs
CAS: 916138-87-9
PubChem: 124490333

» Japanese version   » Back

DBGET integrated database retrieval system